Sexual Health
Human Genome Sciences, Inc. (Nasdaq: HGSI) announced that it has submitted a Biologics License Application (BLA) to the U.S. Food and Drug Administration (FDA) for its human monoclonal antibody drug ABthrax(TM) (raxibacumab) for the treatment of inhalation anthrax.
Boston Scientific Corporation (NYSE: BSX) announced the start of patient enrollment in the ORION clinical trial, which is designed to evaluate the Company"s EPIC(TM) Self-Expanding Nitinol Stent System for the treatment of iliac artery disease, a form of peripheral artery disease that impacts a patient"s lower extremities. The first U.S. patient was enrolled on May 14 by Nicolas W. Shammas, M.D., at Trinity Terrace Park Hospital in Bettendorf, Iowa.
A new study of nearly 14,000 U.S. women reveals that those who are in physically abusive relationships are at higher risk for HIV infection.
"Nature" journals are synonymous with the very best in research. Earlier this year, an article by University of Leicester bioengineer Professor Rodrigo Quian Quiroga not only appeared in Nature Reviews Neuroscience, but also featured on the magazine cover. In the article, Prof. Quian Quiroga and co-author Dr. Stefano Panzeri discuss new methodologies that are enabling scientists to better understand how our brain processes information.
Alkermes, Inc. (NASDAQ: ALKS) announced the initiation of two new clinical trials of ALKS 33, an oral opioid modulator for the potential treatment of addiction and other nervous system disorders. Study ALK33-004 is a phase 1 clinical trial designed to examine the ability of ALKS 33 to block the effects of an opioid following a single oral dose of ALKS 33 in healthy, non-dependent, opioid-experienced subjects. Study ALK33-003 is a phase 1 clinical trial designed to evaluate the pharmacokinetics, safety and tolerability of multiple doses of ALKS 33 in healthy volunteers.
The Heatwave Plan has been updated to advise those suffering breathing problems that although ozone levels increase in hot weather, they drop in the evening. People with respiratory problems should stay inside during the hottest part of the day and windows should be kept shaded and closed when the temperature is hotter outside than inside.
According to the US Centers for Disease Control and Prevention (CDC), vaccination with seasonal flu vaccines made for the 2005 to 2009
The Washington Times recently published an opinion piece and an editorial discussing President Obama"s nomination of Indiana University law professor Dawn Johnsen to head the Office of Legal Counsel in the Justice Department. Summaries appear below. ~ Mickey Edwards/William Sessions, Washington Times: The Senate should "act expeditiously to approve" Johnsen"s nomination because "her views on the limits of presidential power are precisely what the Constitution envisions and conservatives have long championed," Edwards, vice president of the Aspen Institute and author of "Reclaiming Conservatism," and Sessions, a partner at the law firm Holland & Knight, write in a Times opinion piece. According to the authors, Johnsen "made her views clear" on the limits of presidential power when she joined a bipartisan group of lawyers that declared that the Office of Legal Counsel should promote "presidential adherence to the rule of law." Edwards and Sessions write that Johnsen is being criticized for "being blunt, unserious and critical of presidential policies." However, these attacks are unwarranted, they write, noting that in the legal profession, "a little blunt talk to a client -- in this case, the president of the United States -- might be required." Edwards and Sessions continue, "What is needed in the Office of Legal Counsel is a person with the constitutional understanding to know that even presidents with whose politics she agrees must obey both the Constitution and federal statutes and who has the gumption to say so, even if the advice won"t be well received" (Edwards/Sessions, Washington Times, 5/21).~ Washington Times: The editorial states that Johnsen "is so radical" that 31 Republican Indiana state senators on Monday sent a letter to Sens. Evan Bayh (D-Ind.) and Dick Lugar (R-Ind.) asking them to oppose her confirmation. The Republican senators called Johnsen"s views supporting abortion rights "extremely radical" and said she often uses "harsh, sensationalizing rhetoric" in her writings on Supreme Court cases, the editorial states. According to the editorial, Johnsen"s "political advocacy shows a profound disregard for the courts" proper role" because she considers the courts "as making up just another political, policymaking branch of government, not as bodies restrained by the Constitution or existing laws." The editorial continues that Johnsen is "guilty" of "asking judges to impose their own policy preferences" in favor of abortion rights "against the dictates of existing constitutional law." The editorial concludes, "Someone with such contemptuous views of the Constitution should not be the Obama administration"s chief constitutional interpreter" (Washington Times, 5/21).
The fitness mantra - Activity, Belief, Confidence, Diet and Exercise.
-- 0 confirmed cases in Wales.
Sens. Richard Burr (R-N.C.), Lamar Alexander (R-Tenn.) and Tom Coburn (R-Okla.) and Reps. Devin Nunes (R-Calif.) and Paul Ryan (R-Wis.) on Wednesday introduced the Patients" Choice Act (S 1099, HR 2520), a counter proposal to Democratic health care reform plans that would create state-based health insurance exchanges and provide U.S. residents tax credits to subsidize coverage premiums, Roll Call reports (Drucker [1], Roll Call, 5/20). The act would require states to separately establish health insurance exchanges made up of private health insurers through which individuals could pick their coverage. The legislation would provide $5,700 in tax credits to families and $2,200 in tax credits to individuals to subsidize coverage premiums, the Washington Times reports (Washington Times, 5/21). An additional $5,000 tax credit would be provided to low-income families (Budoff Brown, Politico, 5/20). The credits would be funded by taxing employer-provided health benefits (Washington Times, 5/21). Under the plan, states would be allowed to shift state residents covered by Medicaid into private coverage (Wayne, CQ Today, 5/20). The measure also would establish a system of health coverage auto-enrollment at emergency departments, motor vehicle departments and through employers (Politico, 5/20). The plan does not establish any new government health care programs (Drucker [1], Roll Call, 5/20). According to Politico, the bill"s sponsors hope to achieve universal coverage for U.S. residents (Politico, 5/20). According to the bill"s sponsors, the plan is budget neutral (Drucker [1], Roll Call, 5/20). Prospects
UK charity the Blood Pressure Association has responded to the publication of revised salt reduction targets by the Food Standards Agency:
HHS and the Department of Justice on Wednesday launched the Health Care Fraud Prevention and Enforcement Action Team to detect and prevent fraud in Medicare and Medicaid, the Washington Post reports (Johnson, Washington Post, 5/21). DOJ also plans to establish teams to address fraud in the Medicare Part D program and CHIP (Kennedy, AP/Houston Chronicle, 5/20). Wednesday"s announcement also included a recommendation by President Obama"s administration to include $311 million in the fiscal year 2010 budget to address health care fraud, which is a 50% increase from FY 2009. According to Attorney General Eric Holder, efforts to combat health care fraud will contribute to the administration"s health care overhaul plans (Clark/Weaver, McClatchy/Kansas City Star, 5/20). The task force, which will include HHS and DOJ staff members, law enforcement agents and prosecutors, will meet biweekly, CQ HealthBeat reports (Norman, CQ HealthBeat, 5/20). Under the plan, existing enforcement teams in Miami and Los Angeles will be expanded and new teams will be established in Houston and Detroit, where officials say suspicious billing patterns have emerged. In addition, the plan will set up task forces in 10 other major cities, which were not named (AP/Houston Chronicle, 5/20). The enforcement teams will increase site visits to durable medical equipment suppliers upon their enrollment. In addition, officials will expand training to help providers identify and prevent fraud or other mistakes (CQ HealthBeat, 5/20). The task force will use electronic claims data to detect "unusual billing problems," according to the Post (Washington Post, 5/21). HHS Secretary Kathleen Sebelius said the task force also intends to simplify billing systems and assist state officials in conducting Medicaid audits (CQ HealthBeat, 5/20). According to Holder, the joint task force will allow officials to share real-time intelligence data on health care fraud by monitoring claims payments, billing patterns and targeted surveillance (AP/Houston Chronicle, 5/20). Money
Former President Clinton has joined efforts to raise money for HIV/AIDS, tuberculosis and malaria from travelers purchasing electronic airline tickets, the New York Times reports. At a press conference in Paris with United Nations special advisor Philippe Douste-Blazy, Clinton said, "If you provide a user-friendly, efficient way of giving, the contributors will use this system."The U.N. is behind the effort, which will enable travelers to voluntarily add a $2 donation for projects to fight malaria, tuberculosis and AIDS when buying an airline ticket, the Times reports. Both Clinton and Douste-Blazy are working with a newly formed group - Leading Innovative Financing for Equity, or LIFE. LIFE is comprised of eight different groups working to raising money for health aid. According to Douste-Blazy, efforts targeting small donors will begin in January 2010. He added that "the idea is that the citizens of the world are connected by the Internet and credit cards and can show their solidarity."The groups also hope to reach people renting cars, booking hotels or buying train tickets, the Times reports (Carvajal, New York Times, 5/21). Clinton said U.S. air passengers will be able to voluntarily participate in the program, adding, "There is no question that huge numbers of people will participate in this. They understand that it doesn"t cost much and that 100% will go to save lives." (AFP/Google.com, 5/20).
A chemical found in green tea might be an effective tool against the sexual transmission of HIV, according to a study conducted by researchers at the University of Heidelberg in Germany and published online in the Proceedings of the National Academy of Sciences, AFP/Google.com reports. According to the study, green tea polyphenol -- called epigallocatechin-3-gallete, or EGCG -- neutralizes a protein in sperm that aids in the transmission of HIV during sex. The researchers noted that they "recently identified a peptide fraction in human semen that consistently enhanced HIV-1 infection." The study found that EGCG is able to neutralize the sperm protein, known as a semen-derived enhancer of virus infection, or SEVI. The researchers said that SEVI is "an important infectivity factor of HIV." According to the researchers, EGCG "appears to be a promising supplement to antiretroviral microbicides to reduce sexual transmission of HIV-1." The researchers said that because a majority of people living with HIV contract the disease through heterosexual transmission and that 96% of new cases are reported in developing and impoverished nations, the use of green tea in topical creams could be a "simple and affordable prevention method" (AFP/Google.com, 5/19).
Reorganizational Healing (ROH), an emerging concept for wellness, healing, and personal growth, is explored in depth in a seminal groundbreaking article and accompanying commentaries in the latest issue of The Journal of Alternative and Complementary Medicine, a peer-reviewed journal published by Mary Ann Liebert, Inc. The Reorganizational Healing articles are available free online at http://www.liebertpub.com/acm.
Women"s reproductive and lifestyle characteristics can be linked to different invasive breast cancer subtypes. Data on 2544 breast cancer cases, presented in the open access journal Breast Cancer Research, suggests that traditional risk factors for development of the condition are associated with different kinds of tumor.
New research provides exciting genetic insight into a rare syndrome that first appeared in the medical literature in the mid 1800s with the case of Julia Pastrana, the world"s most notorious bearded lady. The study, published by Cell Press in the May 21st issue of the American Journal of Human Genetics, reveals intriguing molecular clues about the pathogenesis of this mysterious condition that has captured the attention of the public since the Middle Ages.
Hypertension or high blood pressure is a condition in which the blood pressure in the arteries is chronically elevated. With every heart beat, the heart pumps blood through the arteries to the rest of the body. Blood pressure is the force of blood that is pushing up against the walls of the blood vessels. If the pressure is too high, the heart has to work harder to pump, and this could lead to organ damage and several illnesses such as heart attack, stroke, heart failure, aneurysm, or renal failure.
A class of drugs already approved as cancer treatments might also help to beat alcohol addiction. That"s the conclusion of a discovery in flies of a gene, dubbed happyhour, that has an important and previously unknown role in controlling the insects" response to alcohol.
Three quarters (75%) of women with BV (Bacterial Vaginosis) admit the condition has prevented them from getting intimate with their partner, according to a new survey by Balance ActivTM Vaginal Gel.1 Sufferers reveal BV affects their personal relationships more than any other aspect of their lives, with one in ten sufferers resorting to ending relationships as a result of the embarrassing symptoms.1
Toshiba America Medical Systems, Inc. introduces two advanced multi-detector CT systems, the Aquilion® Premium edition and the Aquilion CX edition. The Aquilion Premium rounds out the company"s CT portfolio to include a product with 160-detector rows and coverage up to 8 cm in a single rotation. This system is also field-upgradeable to an Aquilion ONE. The Aquilion CX is Toshiba"s next generation 64-detector row CT system featuring faster reconstruction standards with up to 28 images per second, Toshiba"s proven Quantum Advantage detector technology and a patient couch that can accommodate up to 660 lbs. The Aquilion Premium and Aquilion CX are both available now.
New research from the US suggests that people who drink from bottles made of polycarbonate plastic, such as that used to make hard-plastic
Type-2 diabetes patients who lose at least 5% of their body weight score significantly higher on health-related quality of life measures than those who gain 5%, according to a new Consumer Health Sciences (CHS) study presented today at the 14th Annual ISPOR (International Society for Pharmacoeconomic and Outcomes Research) Conference in Orlando, Florida. The benefits of weight loss are particularly dramatic for obese patients, who experience a sharp increase in quality of life scores with just a 5% weight reduction.
On World Hepatitis Day, Concateno, a provider of drug testing and medical screening solutions, calls for the increased use of a broader range of Hepatitis testing techniques including dried blood spot and oral fluid testing. The company argues that these cost-effective and easy to use methods are often more convenient than collecting whole blood samples, and could significantly increase screening among injecting drug users (IDUs), one of the highest risk groups for infection.
Vaginal thrush (thrush) is a yeast infection caused by a type of fungus of the candida species, usually Candida albicans. It can affect all women, but is more common among women who are pregnant, those who have weakened immune systems, and women aged 30 to 50. Thrush is generally recurring - it comes back. The fungus, candida albicans, exists naturally in the vagina. As long as it does not multiply too much a woman will not notice it is there. However, if can sometimes multiply to such an extent that it causes swelling of the vagina and vulva.
Bioniche Life Sciences Inc. ("Bioniche"; TSX: BNC), a research-based, technology-driven Canadian biopharmaceutical company, today provided an update on its Phase III clinical program evaluating Urocidin(TM) in the treatment of bladder cancer. On March 31st, the Company announced that recruitment had been completed in its initial Phase III registration trial evaluating Urocidin in the treatment of non-muscle-invasive bladder cancer that is refractory (unresponsive) to the current standard immunotherapy - Bacillus Calmette-Guerin (BCG).
More than 20 million Americans suffer from severe vision loss. While not all eye diseases can be prevented, there are simple steps that everyone can take to help their eyes remain healthy now and reduce their chances of vision loss in the future.
German adolescents are top at boozing! In the current edition of Deutsches Arzteblatt International (Dtsch Arztebl Int 2009; 106 (19): 323 - 8), Martin Stolle et al. of the German Center for Addiction Research in Childhood and Adolescence in Hamburg report that the main change has been the increase in the number of intoxicated girls. In their article, the authors present motivating short-term interventions to counteract secondary problems.
Metabolic Solutions Development Company (MSDC) announced that its lead compound, MSDC-0160, can improve insulin sensitivity and lower blood glucose levels in humans without the side effects of current therapies when taken over a 28-day period, according to preliminary data derived from the company"s Phase IIa clinical trial.
In selecting a Supreme Court nominee, President Obama will have a more diverse pool of judges to choose from than his predecessors did, largely because the number of women on the federal bench has increased dramatically over the past two decades, the AP/Kansas City Star reports. Just two of the 110 justices that have served on the Supreme Court are women: former Justice Sandra Day O"Connor and current Justice Ruth Bader Ginsburg. Most of the candidates Obama is considering are women.According to the AP/Star, there are 212 full-time female judges serving in the federal courts, meaning that women make up more than one quarter of the federal judiciary. In contrast, there were about 40 female federal judges during the Reagan administration. In addition, women make up at least 40% of the judges on 22 of the 53 state supreme courts, another likely for nominees. The AP/Star reports that the increase in the number of female judges reflects the rise in the number of practicing female lawyers; women currently account for about one-third of lawyers and nearly half of all law school graduates. Marcia Greenberger, co-president of the National Women"s Law Center, said, "I wouldn"t say the doors have swung open as fully as we would like." She added, "Nonetheless, there are superb women in the judiciary, academia and private practice."The AP/Star also reports that Obama might seek to increase racial diversity on the Supreme Court, as only two of the 110 justices have been black men: current Justice Clarence Thomas and former Justice Thurgood Marshall. There has never been a Hispanic, Asian-American or American Indian justice (Sherman, AP/Kansas City Star, 5/20).
One well-known and often deadly consequence of alcohol intoxication is impaired driving. Yet still today, it is difficult for even trained observers to fully identify "intoxication," given that so many factors contribute to it. This review examines the very definition of intoxication, as well as methods designed to prevent impaired driving.
Senate Finance Committee Chair Max Baucus (D-Mont.) on Thursday said that Congress" health care overhaul plan would cover 94% to 96% of the population but not undocumented immigrants, the AP/Las Vegas Sun reports (Alonso-Zaldivar, AP/Las Vegas Sun, 5/21). In remarks at a briefing sponsored by the Kaiser Family Foundation, Families USA and the National Federation of Independent Business, Baucus said, "There are always going to be some people ... you just can"t find" to enroll, adding that "we"re going to try to get as close as we can (to 100% coverage) and we"re working hard to accomplish that." He added, "[W]e"re not going to cover undocumented workers. That"s too politically explosive" (Reichard, CQ HealthBeat, 5/21). According to an analysis by the Center for Immigration Studies and the U.S. Census Bureau, undocumented immigrants make up between 15% and 22% of the estimated 47 million U.S. residents without health coverage. Baucus said, "I don"t have a good answer yet to undocumented workers, illegal aliens," adding, "There will still be charity care " (Landers, Dallas Morning News, 5/22). Baucus said that the bill his committee is working on and that he expects to mark up in mid-June will include "incentives" and possibly requirements for employers to pay for employee health insurance. Baucus mentioned the possibility of including an individual mandate and establishing a health insurance exchange (AP/Las Vegas Sun, 5/21). Baucus also noted that the plan most likely will include a public health insurance option in some form (Tumulty, "Swampland," Time Magazine, 5/21). "Everything"s on the table," Baucus said, warning that "because this is so big, so complex, there are going to be a lot of trade-offs. ... This is just so large" (CQ HealthBeat, 5/21). He said that he is very optimistic about the prospects of bipartisan support for the legislation, placing the odds at between 75% and 80% ("Swampland," Time Magazine, 5/21).
Summaries of several developments related to health care reform appear below.
Pregnant women with low levels of vitamin D may be more likely to suffer from bacterial vaginosis (BV) - a common vaginal infection that increases a woman"s risk for preterm delivery, according to a University of Pittsburgh study. Available online and published in the June issue of the Journal of Nutrition, the study may explain why African-American women, who often lack adequate vitamin D, are three times more likely than white women to develop BV.
Results presented today at the 162nd American Psychiatric Association (APA) congress in San Francisco, CA, demonstrated the efficacy and tolerability of SEROQUEL® (quetiapine fumarate) for treating depressive episodes in bipolar disorder, including the difficult-to-treat bipolar II patient population.1,2 The data are from combined analyses of four large-scale clinical trials to examine SEROQUEL as a treatment for depressive episodes associated with bipolar I and II disorders. SEROQUEL and SEROQUEL XR™, a once-daily, extended-release formulation of SEROQUEL, is one of the most widely studied atypical antipsychotic in bipolar depression and the only agent approved as monotherapy to treat the spectrum of mood episodes associated with bipolar disorder.
InVitria"s Director of Cell Culture, Dr. Steve Pettit, will present the performance enhancing features of ZAP-CHO, a new media component for Chinese hamster ovary (CHO) cell culture, at 3:30 pm on Wednesday, May 20, 2009 as part of BioProcess International"s BioProcess Theatre, a venue employed to facilitate the sharing of advances and discoveries in the biopharmaceutical sector.
Couples are being asked to replace their usual form of birth control with a new male contraceptive in a study to test its effectiveness.
Following the lead of the Needlestick Safety and Prevention Act in the U.S., government regulations regarding syringe needle handling and disposal continue to proliferate worldwide, fostering increased demand in the use of safety syringes. Retractable syringes represent the most elegant approach to addressing the caregiver sharps risk issue by lowering the risk of user error and de-emphasizing the need for a separate sharps disposal step.
Mr Secretary General, Madame Director General, Ladies and Gentlemen, we are gathered here today in the shadow of the pandemic influenza threat posed by the Novel A / H1N1 virus.
Cancer Research UK scientists have tamed a virus so that it attacks and destroys cancer cells but does not harm healthy cells, according to a paper published in PLoS Pathogens*.
A first-of-its-kind report released today by the national consumer health organization Families USA analyzes the Tennessee health care plan CoverTN, spotlights numerous problems with the plan, and calls CoverTN a bad model for other states to follow as they seek to assist their own uninsured residents.
Royal Philips Electronics (NYSE: PHG, AEX: PHI) introduced three new respiratory support devices: the Respironics V60 and V200, and Trilogy100 ventilators. These ventilation solutions are intended to support breathing in the intensive care, sub-acute, and home care settings. As a family of products, the three devices are well-suited to address the ventilation care challenges that clinicians face on a daily basis, such as treating respiratory failure from exacerbations of chronic obstructive pulmonary disease (COPD) while avoiding ventilator-associated pneumonia.
The American Pharmacists Association (APhA) is pleased to announce that Joseph P. Vande Griend, PharmD, BCPS, of Denver, Colorado, is the recipient of the 2009 APhA Clinical Research Paper Award. The award was presented during the APhA Annual Meeting and Exposition in San Antonio, Texas, April 3-6, 2009.
In a study of 130 overweight adolescents, researchers at the University of California, San Diego School of Medicine found that frequent self-weighing is associated with positive behaviors and may prove to be a useful weight-control tool.
Pediatricians now have a new and simple way to diagnose a serious problem facing our nation"s children - thanks to David Kaelber, M.D., Ph.D., M.P.H., MetroHealth System pediatrician, internist, and chief medical informatics officer and Case Western Reserve University School of Medicine researcher and faculty member. Nearly 75% of cases of hypertension and 90% of cases of prehypertension in children and adolescents go undiagnosed. These troubling statistics were documented in previously published research by Dr. Kaelber. From this research, Dr. Kaelber and fellow researchers felt that one of the main reasons for the under-diagnosis may be due to the complex chart currently used to help physicians and medical personnel identify high blood pressure in children. So Dr. Kaelber"s team simplified the chart - focusing solely on a child"s age and gender - eliminating the need for a height percentile and reducing the number of values in the blood pressure table from 476 to just 64. The revised chart and accompanying description are published in the June issue of the journal Pediatrics.
According to a new position statement from the National Athletic Trainers" Association (NATA), proper management of acute spinal injuries on the athletic playing field is crucial, given that sports participation constitutes the second most common cause of spinal cord injuries for Americans age 30 and younger. Sports medicine providers and others on the sidelines need to be familiar with the appropriate acute-management guidelines for athletes with cervical-spine injuries. Published in this month"s Journal of Athletic Training, NATA"s scientific publication, the position statement provides detailed guidelines for the immediate treatment and transport of athletes who are injured on the playing field.
A study of 3,133 men from a variety of test centres across Europe has shown that lower 25 (OH) D levels (vitamin D levels) were associated with poorer brain performance (in middle aged and older men). The study looked at a number of cognitive function tests with only one being linked to vitamin D statistically. The study did not look at cognitive function in women.
Medimix International, a leader in global healthcare marketing research for life sciences industry, announced that it will be exhibiting at the 45th AGM of the American Society of Clinical Oncology, which will take place in Orlando, Florida from May 29-June 2, 2009. The annual ASCO meeting is considered to be the premier educational and scientific event in the oncology community, a forum for cutting-edge scientific and educational developments in oncology with a focus on personalizing cancer care.
Matrox Graphics Inc., the leading manufacturer of specialized graphics solutions, announced that QUBYX has integrated DATACOLOR"s Spyder3 colorimeter into its PerfectLUM medical display calibration software. In addition, the calibration software will also support the Matrox Xenia(tm) Series onboard 13-bit Gamma and Digital Luminance Correction (DLC(tm)) technology. By combining each company"s extensive and high quality solutions, Matrox has created a comprehensive package for the medical display and imaging marketplace that will ultimately save time, money, and improve efficiencies in patient care.
When you think of continuing education for nursing, you may imagine medical textbooks, complicated graphs and loads of acronyms. Well, Amy Glenn Vega hopes to transform continuing education by taking nursing lessons and crafting them into steamy page-turners nurses can read while cozying up next to the fireplace in their favorite comfy chairs.
Fibroids are non-cancerous (benign) tumors that grow from the muscle layers of the uterus (womb). They are also known as uterine fibroids, myomas, or fibromyomas. The singular of uterine fibroids is Uterine Fibroma. Fibroids are growths of smooth muscle and fibrous tissue. Fibroids can vary in size, from that of a bean to as large as a melon.
A family-based prevention program designed to help adolescents avoid substance use and other risky behavior proved especially effective for a group of young teens with a genetic risk factor contributing toward such behavior, according to a new study by researchers at the University of Georgia. The National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute on Drug Abuse (NIDA), components of the National Institutes of Health, supported the study, which appears in the May/June issue of Child Development.
Viruses are molecular marauders, plundering cells for the res they
A proposal by a team of UC Davis scientists to develop the world"s first electron microscope capable of filming live biological processes has been awarded a $2 million grant from the National Institutes of Health.
If the heart muscle does not have enough blood (and consequently oxygen) it dies and a heart attack occurs. Another name for a heart attack is myocardial infarction, cardiac infarction and coronary thrombosis. According to Medilexicon"s medical dictionary, a heart attack is "infarction of a segment of heart muscle, usually due to occlusion of a coronary artery". (Infarction = the process whereby an area of dead tissue is caused by a loss of blood supply).
A drug currently FDA-approved for use in diabetes shows some protective effects in the brains of patients with relapsing remitting multiple sclerosis, researchers at the University of Illinois at Chicago College of Medicine report in a study currently available online in the Journal of Neuroimmunology.
Accumetrics, Inc. announces that it has enrolled its 1,000th patient
Restricting carbohydrates, regardless of weight loss, appears to slow the growth of prostate tumors, according to an animal study being published this week by researchers in the Duke Prostate Center.
Researchers at Boston University School of Medicine (BUSM) and Boston University School of Public Health have found that no adjustment method fully resolves confounding by indication in observational studies, meaning when the validity of a study is threatened by unmeasured confounding, it is not straightforward to determine which method of adjustment, if any, is most effective in obtaining a valid and precise estimate of effect. The study appears online in the Journal of Clinical Epidemiology.
A study led by researchers at Fred Hutchinson Cancer Research Center has identified two proteins in the blood that could become important prognostic markers for long-term survival in breast cancer patients. The proteins are associated with chronic inflammation, which is known to contribute to cancer development and progression.
Cancer patients treated with the widely used drug bevacizumab (Avastin) in combination with chemotherapy are at greater risk of life-thereatening gastrointestinal (GI) perforations. This is the conclusion of Shenhong Wu, M.D., Ph.D., Principal Investigator, and colleagues at Stony Brook University Medical Center, in a study published online and in the June print issue of The Lancet Oncology.
The key to reducing the leading cause of pediatric emergency room visits could be to educate young patients and their parents about how to manage asthma, according to an updated review of studies. Moreover, such programs could lead to fewer hospitalizations for children.
Better science, better regulation and better access policies are needed in Europe to support an
The potential of using stem cells to treat Alzheimer"s disease and other illnesses will be investigated by Victorian and Californian researchers under a US$22 million (US$28.7 million) collaboration, Innovation Minister Gavin Jennings said recently.
The American College of Medical Genetics (ACMG) has joined the Association for Molecular Pathology, the College of American Pathologists, and the American Society for Clinical Pathology in a lawsuit filed today charging that patents on the human genes associated with breast and ovarian cancer interfere with diagnostic testing, stifle research and limit women"s options regarding their health care. The lawsuit challenges patents on the BRCA1 and BRCA2 genes, which are responsible for most cases of hereditary breast and ovarian cancers. Because these genes are "products of nature," the ACMG believes that granting patents on them is illegal.
How well health care industry groups follow through on their "homework assignment" from President Obama to submit specific plans by early June on how they intend to reduce health care spending growth by $2 trillion over the next decade could determine whether current attempts to develop health care overhaul legislation are successful, the AP/Contra Costa Times reports (Alonso-Zaldivar, AP/Contra Costa Times, 5/25).In a letter that was sent to Obama on May 10, a coalition of health care industry groups wrote, "We will do our part to achieve your administration"s goal of decreasing by 1.5 percentage points the annual health care spending growth rate. ... This represents more than a 20% reduction in the projected rate of growth." The letter -- which was signed by the American Medical Association, the American Hospital Association, Pharmaceutical Research and Manufacturers of America, the Advanced Medical Technology Association, America"s Health Insurance Plans and the Service Employees International Union -- did not elaborate on what specific measures the groups would take to achieve such reductions. The Obama administration requested specifics on the coalition"s cost-cutting plans by June 1 (Kaiser Daily Health Policy Report, 5/18).Each group has been looking into its own ways it can reduce spending growth, the AP/Contra Costa Times reports. Insurers currently are examining strategies to cut the administrative costs of filing claims. AMA President-elect James Rohack said his organization will look at how to implement comparative effectiveness research and ways to prevent harmful and costly drug interactions, which he said "can save money ... by preventing unnecessary readmissions to hospitals," adding, "The most costly site where patients get care is the hospital." In addition, hospitals have begun looking into how to reduce readmissions.If the industry groups are able to convince lawmakers that their plans can significantly reduce spending growth, Obama "could be well on his way to closing a deal with Congress" on universal health coverage, the AP/Contra Costa Times reports. However, if the plans are rejected, the groups risk their reputations and Obama could be "seen as naive for entertaining such promises," according to the AP/Contra Costa Times. Some experts have said that the groups" pledge to cut health care spending is possible "in theory." According to the AP/Contra Costa Times, the challenge will be to persuade medical providers "to change years of ingrained habits that lead to much of the wasteful spending" in the health care system (AP/Contra Costa Times, 5/25). AHIP"s Ignagni Profiled
The Excellence in Oncology Awards (EinO) 2009 are now open for entry. The Awards, now in their fourth year, recognise and reward best practice in oncology management, education and patient care throughout the UK. Winners will be announced at a prestigious dinner on 6 October 2009 during the National Cancer Research Institute (NCRI) Cancer Conference.
About half of terminally ill patients do not have discussions with their physicians regarding end-of-life choices, according to a Harvard Medical School study published in the Archives of Internal Medicine, the Boston Globe reports.The study, funded by the National Cancer Institute, examined files on 1,517 patients in California, Iowa and Alabama with metastasized lung cancer. According to the Globe, a majority of patients diagnosed with metastasized lung cancer do not survive two years. Researchers asked the patients whether a physician or other health care provider had recommended hospice care or discussed end-of-life care preferences with them. According to the study, about 49% of blacks and 43% of Hispanics had discussed end-of-life care preferences with a physician or health care provider within four to seven months of their diagnosis, compared with 53% of whites and 57% of Asians. Lead study author Haiden Huskamp, an associate professor at Harvard Medical School, said, "Patients who had unrealistic expectations about how long they had to live were much less likely to talk about hospice with their doctor." Huskamp theorized that patients who said they did not discuss end-of-life options with providers might not have completely understood their prognosis or chose to believe in a better outcome. Huskamp also said physicians typically are not well-trained to handle some delicate conversations (Lazar, Boston Globe, 5/26).
Children"s behavior is determined, in part, by their genes and by the settings in which they develop. A new longitudinal study describes how a family-based prevention program helped rural African American teens avoid engaging in risky behaviors, even if some of them may have had a genetic risk to do so.
The Armed Forces Pay Review Body has announced that military doctors and dentists will receive a 1.5% pay rise this year, significantly lower than the 2.8% awarded to other armed forces personnel. There are serious manpower problems in the Defence Medical Services. The BMA is concerned that the announcement will have an adverse effect on the recruitment and retention of armed forces doctors.
A new analysis by AARP"s Public Policy
U.S. Senator Mel Martinez (R-FL) introduced an effort aimed at updating the U.S. Census" current function questions to better improve our nation"s long-term care services and support systems. By replacing a small portion of the survey with standardized function questions used by medical providers, the Disability Data Modernization Act will provide more accurately collected data used for planning the future health care needs of elderly and disabled Americans.
May is Healthy Vision Month, which in 2009 focuses on the 60 percent of Americans who have refractive vision problems.
Madeleine Bordallo, the U.S. delegate from Guam, has introduced legislation that would fund a survey to collect health data from Native Hawaiians and Pacific Islanders, the Pacific Daily News reports. The legislation would amend the Public Health Service Act to fund the survey through HHS.Bordallo said, "Native Hawaiian and Pacific Islander communities are eager to move forward with their efforts to improve public health. This scientific survey would establish baseline health information to inform health policy and interventions so that individual and community health can be properly tracked and evaluated." According to the Daily News, while federal agencies should be collecting data on native Hawaiians and Pacific Islanders separately from Asian-Americans, most have not done so (Limtiaco, Pacific Daily News, 5/26).
The new project is an interdisciplinary research project covering the neurobiological and socio-psychological causes of obesity. It has been awarded EUR 6 million from the EU, corresponding to just over SEK 60 million. The project will gather scientists from seven countries, and will be co-ordinated from the Sahlgrenska Academy.
ONCOLOGY: Targeting the more lethal form of the cancer rhabdomyosarcoma
A group of fertility experts, who pioneered the development of Preimplantation Genetic Screening (PGS), are sharing the step-by-step best practices and explaining what errors can be made along the way.
An international team of scientists studying a rare genetic disease discovered that a bundle of proteins with the long-established function of keeping chromosomes together also plays an important role in regulating genes in humans.
Kinex Pharmaceuticals will present results from a Phase 1 clinical study with KX2-391, at the ASCO 2009 Annual Meeting in Orlando, on May 29, 2009. The study was carried out at MD Anderson, Roswell Park Cancer Institute (RPCI) and Fox Chase Cancer Center. Dr. Alex Adjei, the Principal Investigator from RPCI will deliver the presentation entitled "Results of a phase I trial of KX2-391, a novel non-ATP competitive substrate-pocket directed SRC inhibitor, in patients with advanced malignancies."
Senesco Technologies, Inc. ("Senesco" or the "Company") (NYSE Amex: SNT) announced that Richard Dondero, Vice President of Research and Development, will be presenting pre-clinical data from Senesco"s multiple myeloma studies at the 12th Annual Meeting of the American Society of Gene Therapy, which is being held at the San Diego Convention Center in San Diego, CA, from Wednesday, May 27th through to Saturday, May 30th, 2009. Mr. Dondero will be presenting in the afternoon session on Thursday, May 28th.
Two newspapers recently published opinion pieces on abortion-related public opinion polls. Summaries appear below.~ Steven Kull, Baltimore Sun: Although "many Americans feel morally conflicted about" abortion, it is a "common error to believe that the American electorate is deeply divided about how the government should deal with" the procedure, Kull -- director of WorldPublicOpinion.org and the Program on International Policy Attitudes at the University of Maryland -- writes in a Sun opinion piece. He adds that "there is substantial consensus that the government should not criminalize abortion." According to Kull, a new CNN poll found that 68% of respondents believe Roe v. Wade should not be overturned, and a recent WorldPublicOpinion.org poll found that when asked, "Do you think the government should be involved in trying to discourage abortion or do you think the government should leave these matters to the individual," 69% said that the matter should be left to the individual. Kull adds that "of the 29% who said that the government should be involved in trying to discourage abortions, a remarkably low 8% favored using criminal enforcement methods." According to Kull, other polls have found if "given a middle option -- somewhere between strict prohibition and government permission -- a significant number will choose it." Kull writes that "once the moral question is differentiated from the question of how the government should act, it does appear that there is substantial consensus that abortion should not be criminalized." He concludes, "Once the option of criminal enforcement is taken off the table, constructive options are more likely to emerge and can be an effective focus for the energies freed up from the incessant debates about abortion" (Kull, Baltimore Sun, 5/22).~ Cheryl Wetzstein, Washington Times: "It"s rather ironic that as the most pro-choice government in U.S. history settles into its seats," a Gallup poll "finds that most Americans are pro-life," columnist Wetzstein writes in a Times opinion piece. She adds, "Some observers have tried to pooh-pooh this result, but it doesn"t surprise me for two reasons." Wetzstein writes that her "experience with youth, both personally and professionally, is that they often recoil at abortion," adding, "So I find a pro-life trend in youth to be quite plausible." She continues, "Second, I think some aging baby boomers are changing their views," adding, "People generally become more conservative and self-reflective with age. Legacies matter. Hindsight is 20/20. Regrets appear." Wetzstein concludes, "My suspicion is that in more than a few cases, baby boomers who were willing to have abortions are not at ease with the idea of losing their grandchildren," adding, "It may be that in the autumn of life, being "pro-life" has a whole new meaning" (Wetzstein, Washington Times, 5/26).
U.S. antitrust laws could affect health care industry groups" efforts to work together to rein in health care costs, the New York Times reports (Pear, New York Times, 5/27). In a letter sent to President Obama on May 10, a coalition of groups -- the American Medical Association, the American Hospital Association, Pharmaceutical Research and Manufacturers of America, the Advanced Medical Technology Association, America"s Health Insurance Plans and the Service Employees International Union -- pledged to reduce the annual health care spending growth rate by 1.5%. The groups did not elaborate on what specific measures they would use to achieve such reductions, but the Obama administration has requested specific plans from the groups by June 1 (Kaiser Daily Health Policy Report, 5/26). According to the Times, many of the plans being considered by the health care industry would require greater cooperation across health care providers. Robert Leibenluft, a former Federal Trade Commission official, said, "Any agreement among competitors with regard to prices or price increases -- even if they set a maximum -- would raise legal concerns." In addition, while Obama is asking for specific plans from the health care industry, the administration has not offered any relief from antitrust laws, the Times reports. Furthermore, during his campaign Obama pledged to increase enforcement of antitrust laws, according to the Times.Antitrust laws have had a negative effect on previous health reform efforts, the Times reports. In 1993, the drug industry established a voluntary cost control plan that limited each drug company"s annual increase in the average price of prescription drugs to the increase in the Consumer Price Index, but the Department of Justice ruled that the proposal would violate antitrust laws. DOJ officials said that the U.S. Supreme Court made it clear that setting price maximums was akin to setting price minimums, which is illegal. In a letter to the Senate Finance Committee, AHA wrote that uncertainty regarding the enforcement of antitrust laws "makes it difficult for a hospital and doctors to collaborate to improve care" and reduce costs. AMA has asked Congress to amend antitrust laws to allow physicians to collectively negotiate with insurers over fees and other concerns, but FTC repeatedly has designated the practice illegal price-fixing, according to the Times. FTC officials said that consumers could benefit from cooperation among health care industry groups but that cooperation also could lead to increased bargaining power for physicians and hospitals, making it easier for them to set prices and eliminate competition (New York Times, 5/27). Reform Developments
Over the next 18 months, psychiatrists will revise the American Psychiatric Association"s Diagnostic and Statistical Manual of Mental Disorders, which is used to determine how U.S. residents" mental health is assessed, diagnosed and treated, the Los Angeles Times reports. Since the manual was last updated in 1994, technologies such as brain imaging and new understandings of the biological and genetic causes of many disorders have "almost guaranteed alterations" in the number of mental disorders included in fifth DSM volume, which is scheduled to be published in 2012, the Times reports.While some psychiatrists argue the manual should be broad enough to determine treatment for those who need it, others are concerned that if too broad, the manual will diagnose conditions that would otherwise be considered normal human behavior. David Kupfer, a psychiatrist at the University of Pittsburgh"s Western Psychiatric Institute and Clinics and chair of the DSM-V task force, said the DSM-V will recognize variations of disorders that have not been seen as part of "classic" illnesses, and will describe disorders in more detail, including how they differ based on race, gender, age, physical health and culture. Health insurance companies use the manual to determine coverage options for certain treatments.People involved in the revisions said the manual will be a better reflection of mental conditions of "real" people, rather than just those with the most severe cases of disorders or obvious diagnoses, the Times reports (Roan, Los Angeles Times, 5/26).
The Rwanda Ministry of Youth recently launched a six-month campaign aimed at reducing the trend of cross-generational sex, which some health officials say is contributing to the spread of HIV among young people in the country, the New Times/AllAfrica.com reports. Rwanda"s National Commission for the Fight Against AIDS, USAID and Population Services International launched the campaign urging youth to avoid having sex with older people. The minister of youth, Protais Mitali, said that all institutions in the country should help address the trend in order to curb the spread of HIV among young people. According to Anita Asiimwe, executive secretary of the commission, data show that Rwandan women ages 20 to 24 are five times more likely to be HIV-positive than men their age. She added that statistics indicate that one out of every 10 girls had her first sexual experience with a man 10 or more years older. She added, "Since older men are much more likely to be [HIV-positive] than their male counterparts, young girls appear to be getting infected by older men, rather than by boys of their age." Staci Leuschuer with PSI Rwanda said that there are lower rates of condom use among young people, noting that about 40% of young people report condom use and that about 24% to 25% of girls ages 15 to 24 are using condoms (Mutara, New Times/AllAfrica.com, 5/24).
The Lance Armstrong Foundation (LAF) and Penn Medicine have announced a four-year partnership to further develop and disseminate the LIVESTRONG Care Plan Powered by Penn Medicine"s OncoLink. This free service gives cancer survivors, their families and physicians the ability to create an individualized plan of care using up-to-date treatment information based on Institute of Medicine recommendations, as well educating them about their options to maintain optimal health once they are out of treatment.
The Lung Association congratulates Health Minister Leona Aglukkaq and the Government of Canada on its announcement of imminent changes to the federal Tobacco Act that include:
In the rat race of life, one thing is certain: there"s no place like home.
The majority of men who receive one of the standard treatments for localized prostate cancer - surgery or radiation therapy - have an excellent outcome.
Genital herpes is a sexually transmitted infected caused by HSV (herpes simplex virus). This virus affects the genitals, the cervix, as well as the skin in other parts of the body. There are two types of herpes simplex viruses: a) HSVp1, or Herpes Type 1, and b) HSV-2, or Herpes Type 2.
Assisted reproductive technology (ART) is responsible for an estimated 219,000 to 246,000 babies born each year worldwide according to an international study. The study also finds that the number of ART procedures is growing steadily: in just two years (from 2000 to 2002) ART activity increased by more than 25%.
In support of National Hurricane Preparedness Week, Hydration Technology Innovations (HTI) (www.htiwater.com) aims to educate people about a proprietary water filtration system that was created in conjunction with NASA and the Department of Defense, and is being used by disaster relief organizations and branches of the United States military.
Walsall Hospitals NHS Trust has "gone-live" with Horizon Enterprise Visibility; a visual control system designed specifically for hospitals, from healthcare IT solutions and services specialists, McKesson. Via real-time access to patient information, Walsall will be using Horizon Enterprise Visibility to improve re efficiency and bed utilisation to reduce costs and improve the quality of patient care.
As the credit crunch keeps on crunching and finances are squeezed ever tighter it is tempting to put off that visit to the optometrist and to carry on with your old specs for another few months. If your vision is good then it is even less likely that you will make an appointment for a sight test - after all you can "see" that nothing is wrong!
MAP Pharmaceuticals, Inc. (Nasdaq: MAPP) announced that the efficacy portion of its first Phase 3 clinical trial evaluating its novel LEVADEX™ orally inhaled migraine therapy met all four primary endpoints. Additional endpoints showed that LEVADEX provided rapid and sustained pain relief for up to 48 hours after dosing.