Medical Devices
Bosentan appears to be a more cost-effective initial treatment option for patients with moderate pulmonary arterial hypertension (PAH), classified as WHO functional class III, than no active intervention.
"President Barack Obama on Wednesday rejected the idea of fully taxing Americans" employer-provided health insurance benefits, but suggested he might be persuaded to tax so-called Cadillac coverage ... in the interest of a compromise with Congress," McClatchy/The Star-Telegram reports. The President, speaking at a "town hall-style event" taped at the White House and aired on ABC News, "said he would prefer to pay for expanded coverage by eliminating some deductions for higher-earning taxpayers but that "there"s going to have to be some compromise." The President "said he understands Americans" trepidation about changing the system: "They know that they"re living with the devil, but the devil they know they think may be better than the devil they don"t." He said any reform would be phased in, not happen overnight" (Talev and Lightman, 6/24).
The Associated Press reports on the costs of disease prevention: "When it comes to health care spending, an ounce of prevention is seldom worth a pound of cure. ...The truth is, shockingly few prevention efforts actually save the health care system money overall, despite claims by the president and some in Congress."
AdvanDx announced it received FDA 510(k) clearance for GBS PNA FISH® for detection of Streptococcus agalactiae, aka Group B Strep, from turbid Lim Broths inoculated with vaginal and rectal swabs obtained from pregnant women between 35 and 37 weeks gestation. The 90 minute molecular diagnostic test enables rapid and highly sensitive detection of Group B Strep from Lim Broths to help detect colonization in pregnant women.
At the opening of a three-day U.N. financial summit on Wednesday, developing countries joined U.N. officials in "calling for more money and a greater role in regulating the world economy in the wake of the worst global financial crisis since the Great Depression, which has taken a disproportionate toll on poor nations," AP/Google.com reports (Astor, AP/Google.com, 6/25).
The following summarizes recent editorials and opinion pieces responding to health reform action over the last week.
The Denver Post on Friday examined efforts to establish needle-exchange programs in Colorado to reduce the risk of HIV and hepatitis C among injection drug users. According to the Post, 185 cities in Colorado have needle-exchange programs, but legislation that would have legalized needle exchanges statewide did not advance in the Legislature this year. "The issue is more complex than it perhaps first appears," Evan Dreyer, a spokesperson for Gov. Bill Ritter (D), said, adding that "law enforcement and the Colorado Department of Public Health and Environment both expressed serious reservations" about a proposal that would have legalized needle-exchanges statewide. A coalition of public health officials, treatment providers and advocates are increasing efforts to establish a needle-exchange program in Denver, the Post reports. The Denver Drug Strategy Commission in February recommended that Mayor John Hickenlooper consider a pilot needle-exchange program, DDSC Director Karla Maraccini said. The commission is looking at different programs to develop a model following Hickenlooper"s request for additional research. However, Denver District Attorney Mitch Morrissey has concerns that a local needle-exchange program would violate state law, according to Morrissey"s spokesperson Lynn Kimbrough. Eric Brown, a spokesperson for Hickenlooper, added, "Anything in contradiction to city or state law would have to be carefully considered." Proponents of needle-exchange programs say they prevent HIV and hepatitis C, but opponents say they condone injection drug use. Mark Thrun, director of HIV prevention for Denver Public Health, said, adding that needle-exchange programs prevent IDUs from "getting these chronic, potentially fatal diseases" and give public health workers "an opportunity to link them into treatment; and it lessens the economic burden on the already overburdened health care system." Thrun noted that several studies have found that needle-exchange programs do not encourage or prolong injection drug use and make IDUs more likely to seek treatment. In addition, a 2005 CDC study found that 86% of exchange programs make treatment referrals and that more than 80% offer counseling and testing for HIV/AIDS and hepatitis C.Nancy Steinfurth, executive director of the Hep C Connection, noted that an estimated 10% of HIV cases and 70% of hepatitis C cases are transmitted through needles (Auge, Denver Post, 5/15).
More than 50 further education colleges are set to make redundancies leading to the closure of a huge number of nurseries, according to UNISON, UCU and NUS.
It is now possible to engineer tiny containers the size of a virus to deliver drugs and other materials with almost 100 percent efficiency to targeted cells in the bloodstream.
Condom vending machines will be unveiled on Monday in Dar es Salaam, Tanzania, as part of a six-year pilot HIV prevention initiative in the country, Tanzania"s The Citizen reports. Daniel Crapper of Population Services International said, "We are working very hard to ensure that condoms are widely available to the people." About 100 machines -- at a cost of about 380,000 Kenyan shillings, or $350 -- will be installed in various bars in Dar es Salaam. The project also will be carried out in Morogoro, Iringa and Mbeya before being rolled out to other regions across the country, according to Crapper. "Bars and night clubs are in our targets because they have the highest risk of unsafe sex, especially when people get drunk," Crapper said, adding, "This will enable condoms to be available almost daily." He noted that the condoms will be offered at a lower cost compared with some retail outlets and that the new initiative will not interfere with condom distribution systems throughout the country. According to The Citizen, the condoms will be available for purchase from the vending machines for 100 shillings, or about $1. John Wanyancha, PSI"s HIV/AIDS program manager, said that the project"s leaders focused on targeting areas with high HIV/AIDS rates after research revealed that inaccessibility to condoms at night was a major challenge in efforts to curb the spread of the disease. He noted that about 324 million condoms have been distributed in Tanzania since 2001 (Mbani, The Citizen, 5/15).
A test commonly used to help identify women with diabetes during pregnancy may be an accurate, convenient and inexpensive way to screen the general population for unrecognized diabetes and prediabetes, according to Emory University researchers.
The American Diabetes Association, the nation"s leading health organization in the fight to stop diabetes, is pleased to announce that the National Employment Lawyers Association has honored Gary Branham, who successfully fought discrimination based on diabetes, as one of three "Workplace Heroes & Heroines." The award honors those who have made a difference in the evolution of employee rights, and advancing equality and justice in the American workplace during the past twenty years. (For more information on this award, see http://www.nela.org.)
Researchers at the Intermountain Medical Center have conducted research into the link between atrial fibrillation, a fairly common heart rhythm disorder, and dementia. The study of more than 37,000 shows that patients with atrial fibrillation were 44% more likely to develop dementia than patients without the disorder.
People who eat lots of soy products have better lung function and are less likely to develop the smoking-associated lung disease COPD (Chronic Obstructive Pulmonary Disease). A study published in BioMed Central"s open access journal Respiratory Research has shown that consumption of a wide variety of soy products can be associated with a reduction in the risk of COPD and other respiratory symptoms.
The NMC announced the appointment of Roger Thompson as its new Director of Standards and Registration.
HearAtLast Holdings, Inc. (PINKSHEETS: HRAL), a leading provider of suitable affordable solutions to clients with hearing needs in the billion dollar hearing loss market, announced that in keeping with its tradition of bringing innovative new products to consumers, the Company announces the unveiling of breakthrough hearing products based on the Neuro-Compensator™ algorithm technology from VitaSound Audio.
The Agency for Healthcare Research and Quality"s annual release of state-by-state quality data continues to give states mixed reviews for the quality of care they provide. As in previous years, AHRQ"s 2008 State Snapshots show that no state does well or poorly on all quality measures.
Many animals and people experience chronic joint pain. In dogs, a common of joint pain is hip dysplasia, a developmental defect of the hip joint. Implantation of gold into the soft tissues around the hip joints of dogs with dysplasia can relieve pain and lessen stiffness for several years.
Researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, came a step closer to understanding how cells close gaps not only during embryonic development but also duringwound healing. Their study, published this week in the journal Cell, uncovers a fundamental misconception in the previous explanation for a developmental process called dorsal closure.
NPR began a series of reports on the health care lobbyists who attend Congressional sessions as part of their campaign. Richard Miller, a "longtime lobbyist for the American Chiropractic Association, says it"s important that the chiropractors keep on top of the health care overhaul legislation - and also take pains to make sure that senators and staff see them doing that, because the chiropractors are small dogs in a big fight." President Barack Obama "certainly sees Washington"s lobbyists as an obstacle to change. He"s tried limiting their access to the executive branch, but that runs into the constitutional question." Lobbying is on the rise: "Between 1998 and 2008, the number of registered lobbyists on health care more than doubled, to 3,627, according to the Center for Responsive Politics." Spending also increased: "Organizations lobbying on health care spent $484.4 million in 2008, more than two and a half times the spending in 1998." The project includes an interactive panoramic photo of lobbyists in the Senate HELP Committee hearing room and asks readers to help identify the players (Overby and Seabrook, 6/25).
Transferring heart attack patients to specialized hospitals to undergo angioplasty within six hours after receiving clot-busting drugs reduces the risk of life-threatening complications, according to a Canadian-led study published today. The findings, published in the New England Journal of Medicine, suggest that routine early transfer of patients after clot-busting drugs are administered results in significantly better outcomes than the current practice of transferring patients only when the clot-busting drugs fail.
Kidney transplant patients have a weaker response to influenza immunization than healthy individuals, especially in the first six months after receiving a transplant, according to a study published in the July issue of the American Journal of Kidney Diseases, the official journal of the National Kidney Foundation.
Southampton"s teaching hospitals have been recognised by one of the UK"s top medical organisations for leading the way in use of antibiotics in the fight against infection. The British Medical Association, the professional body for doctors and medical students, praised Southampton University Hospitals NHS Trust"s development of clear and simple antimicrobial prescribing guidelines for staff.
The American Public Health Association (APHA) applauds the House for today passing a comprehensive climate change bill that includes important provisions to protect the health of the public.
Draft proposals by the Productivity Commission designed to reduce the red tape burden on medical practices will benefit patients, the AMA said today.
The Government of Canada is moving forward with proposed regulations to prohibit the advertisement, sale and importation of polycarbonate plastic baby bottles that contain bisphenol A, otherwise known as BPA, to reduce newborn and infant exposure to this substance, announced the Honourable Leona Aglukkaq, Minister of Health.
Diabetes patients who are hospitalized for non-critical illnesses, and develop hypoglycemia while hospitalized, are likely to remain hospitalized longer and face greater risk of mortality both during and after hospitalization, according to a study published in the July issue of Diabetes Care.
The European Medicines Agency (EMEA) has today announced their recommendation to withdraw the marketing authorisations for dextropropoxyphene-containing medicines (including co-proxamol) across the European Union (EU). This recommendation was made after the Committee on Medicinal Products for Human Use (CHMP) concluded that the risks, particularly of potentially fatal overdose, were greater than the medicine"s benefits. The EMEA"s recommendation has been forwarded to the European Commission (EC) for a decision which will be legally binding across the EU. In the UK, the only medicine affected by the EMEA"s announcement is co-proxamol.
Advance in detecting melamine-adulterated food
Biolex Therapeutics, Inc. announced that it has completed patient enrollment in the SELECT-2 Phase 2b trial of its lead product candidate Locteron® for the treatment of chronic hepatitis C. Locteron, controlled-release interferon alpha 2b, is designed to improve patient care by providing a more convenient once-every-two week dosing schedule and by reducing the side effects, including flu-like symptoms, associated with pegylated interferons, the current standard of care.
UNISON and UNITE are calling on North Somerset Council to put a stop to plans to privatise transport services, warning that outsourcing could put vulnerable young children at risk.
Yaupon Therapeutics, a privately held specialty pharmaceutical company, has announced it has completed enrollment for a pivotal Phase 2 clinical trial for Clearazide for the treatment of early-stage cutaneous T-cell lymphoma (CTCL - stages 1-2a). The study, which is being conducted under a Special Protocol Assessment (SPA) with the FDA, has enrolled 260 patients in 13 of the top cancer centers in the US. Yaupon expects the last patient to complete treatment in the study by June of 2010 and, assuming positive results, will file its NDA shortly thereafter.
On June 26, 2009 several articles published online in Diabetologia by the European Association for the Study of Diabetes investigated the possible relationship between use of insulin glargine (Lantus, sanofi-aventis) and the development of certain malignancies. The authors themselves, and the accompanying editorial, cautioned against over-interpretation of their limited data and analyses, which precluded them from drawing any firm conclusions. For example, there were contradictory findings among the studies, patient populations were not always comparable, and the duration of observation was short. Nonetheless, since the relationship of type 2 diabetes to cancer is of critical importance, further study is warranted.
New data show that at 24 months, patients in the chronic phase of Philadelphia chromosome positive (Ph+) chronic myeloid leukaemia (CML) who are intolerant or resistant to current first-line therapy (Glivec) experienced a rapid response and significant reduction in leukaemia burden when treated with 400mg Tasigna twice-daily1. Furthermore, the research shows that the majority of patients in both the chronic and accelerated phases of the disease are still alive at 2 years when treated with Tasigna1,2.
The US Food and Drug Administration (FDA) said yesterday, June 29, that it had found E. coli O157:H7 in a sample of prepackaged Nestlç© Toll
The Retail Advisory Board (RAB) of the National Association of Chain Drug Stores (NACDS) met yesterday during the 2009 NACDS Marketplace Conference to discuss social networking opportunities within their businesses.
Joe Korner, Director of Communications at The Stroke Association said:
Accredited Practising Dietitian and PhD student Janice Sangster has been awarded the Dietitians
For the first time RCN members can get a unique insight into the International Council of Nurses (ICN) Congress care of a daily blog.
The Royal Pharmaceutical Society of Great Britain (RPSGB) has welcomed the appointment of Mr Robert Nicholls CBE as the Chair Designate of the General Pharmaceutical Council (GPhC).
Diabetes UK has so far encouraged more than 10,000 people in the UK to measure their waists and find out if they are at risk of developing Type 2 diabetes with its national Measure Up Roadshow which kicked off on June 3.
Recommendations for how the HHS Office of the Secretary will spend $400 million in funds for patient-centered research, also known as comparative effectiveness research, were released by Federal Coordinating Council for Comparative Effectiveness Research (CER). The report, mandated by the American Recovery and Reinvestment Act, is designed to help the HHS Secretary and lawmakers improve the quality of care for patients, and provide patients and doctors the best information possible to make decisions about health care.
Baxter International Inc. (NYSE:BAX) announced today a definitive agreement with Edwards Lifesciences Corporation (NYSE:EW) under which Baxter will acquire certain assets related to Edwards" hemofiltration product line, also known as Continuous Renal Replacement Therapy (CRRT). The transaction is expected to close in the third quarter of 2009, pending regulatory approvals.
Healthcare workers in South Africa are at a significantly increased risk of developing drug-resistant tuberculosis, or XDR-TB, in a trend which threatens to further exacerbate the already beleaguered healthcare systems in sub-Saharan countries, according to results of a new study. Researchers say the results underscore the urgent need for stringent TB screening policies among healthcare workers in these areas.
Commenting on new figures published yesterday which show that one in 20 deaths are attributable to alcohol, Dr Peter Terry, Chairman of the BMA in Scotland, said:
A Kansas State University researcher is studying the potential health benefits of a specially bred purple sweet potato because its dominant purple color results in an increased amount of anti-cancer components.
New data from an economic analysis presented today at this year"s European Society of Human Reproduction and Embryology (ESHRE) congress showed that, within the parameters of the simulation model used, the in vitro fertilisation (IVF) treatment MENOPUR (highly-purified human menopausal gonatropin or HP-hMG) offered considerable cost-savings over recombinant follicle stimulating hormone (rFSH).1 The cost-effectiveness of HP-hMG compared with rFSH suggested by this data could make it a more attractive choice for use in infertility treatment within a fixed healthcare budget.
Doctors at the Cedars-Sinai Heart Institute announced today the completion of the first procedure in which a patient"s own heart tissue was used to grow specialized heart stem cells that were then injected back into the patient"s heart in an effort to repair and re-grow healthy muscle in a heart that had been injured by a heart attack.
Children and young adults love the thrill of skateboarding. They learn to master their skills of "riding the rail" and "catching air." But according to the American College of Foot and Ankle Surgeons (ACFAS), such tricks, while fun, can be physically demanding and cause serious foot and ankle injuries.
Summer is in full swing, and barbeques are a perfect way to relax, spend time with family and friends, and celebrate the July 4th holiday. To help you better prepare for this popular activity, nutrition experts at The University of Texas M. D. Anderson Cancer Center offer advice on how to barbeque the healthy way.
Lower extremity peripheral arterial disease (PAD) affects more than eight million Americans, with significant risks of limb loss, disability and death. Treatment of lower extremity PAD focuses on restoring normal blood supply to the affected limb. Traditional treatment, such as surgical bypass, is effective but invasive. In recent years, many patients have been treated with newer endovascular interventions, using catheter-based devices to reopen peripheral arteries in a less-invasive fashion. According to past research, it is unclear if these newer treatments are as effective as conventional surgical bypass in preventing amputation.
Physiological changes associated with the metabolic syndrome may play a role in the risk of postmenopausal breast cancer, according to study results published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
Tuberculosis (TB) experts at Johns Hopkins have evidence from a four-year series of experiments in mice that anti-inflammatory drugs could eventually prove effective in treating the highly contagious lung disease, adding to current antibiotic therapies.
The Arthur Labatt Family School of Nursing at The University of Western Ontario has announced a $2 million research chair to address issues surrounding the chronic shortage of registered nurses in Canada and the United States. Dr. Heather Laschinger, Ph.D., was named the first Arthur Labatt Family Nursing Research Chair in Human Re Optimization.
Somerset Partnership NHS Foundation Trust has announced the appointment of a new Non Executive Director to its Board.
PPD, Inc. (NASDAQ: PPDI) today announced that Takeda Pharmaceutical Company Limited issued a news release reporting that Takeda Global Research & Development Center, Inc., its wholly-owned U.S. subsidiary, has received a complete response letter from the U.S. Food and Drug Administration (FDA) regarding its new drug application (NDA) for alogliptin.
A conservative group wants every lawmaker to pledge to read the entire bill for comprehensive health reform before voting.
Senate Democrats and Obama administration officials hoping that preventive care would create federal savings have been disappointed to learn that it does not create expected cost savings.
"Crunching data from published studies, the authors found that treating a lung-cancer patient with Erbitux, a drug that costs $80,000 for an 18-week regimen, prolongs survival by only 1.2 months," the Wall Street Journal reports. The study, which estimates that the life of each American who dies or cancer could be extended by one year at the cost of $440 billion, was published in the Journal of the National Cancer Institute.
Pharmacists Need A Place At The Health Reform Table The Baltimore Sun
Researchers at North Carolina State University and the Georgia Institute of Technology have received a $1.2 million grant from the National Science Foundation to study whether and how video games can boost memory and thinking skills in the elderly - and then to use their findings to develop a prototype video game to do just that.
Responding to the publication of Lord Darzi"s report, High Quality Care for All: Our Journey So Far, Dr Peter Carter, Chief Executive & General Secretary of the Royal College of Nursing (RCN), said:
The nation"s largest veterinary association applauded four members of the U.S. House of Representatives for introducing legislation that confronts public health threats by investing in the public health veterinary workforce
The British Veterinary Association (BVA) has called on Defra to abandon its plans for a new animal health body that will give responsibility for animal health to an independent board and leave responsibility for animal welfare with ministers.
One-step screening for both genetic and chromosomal abnormalities has come a stage closer as scientists announced that an embryo test they have been developing has successfully screened cells taken from spare embryos that were known to have cystic fibrosis.
It is based on detecting short, repetitive DNA segments in the genome of bacteria. Every single bacterial strain has such characteristic repeats. "With this method we are able to identify bacterial strains as well as clarify their genetic relationships. Furthermore, we can show how new pathogenic variants develop," says Manfred Hç¶fle, researcher at the HZI. The results have now been published in the current issue of the scientific journal Applied and Environmental Microbiology. The work is part of the two European Union funded projects "Healthy Water" and "AQUA-chip". Manfred Hç¶fle is coordinator of both projects that deal with various aspects of the microbiological safety of both, drinking water and sea water.
A new report from the Institute of Medicine recommends 100 health topics that should get priority attention and funding from a new national research effort to identify which health care services work best. It also spells out actions and res needed to ensure that this comparative effectiveness research initiative will be a sustained effort with a continuous process for updating priorities as needed and that the results are put into clinical practice.
People with ankle injuries who do not respond successfully to initial treatment may have a second chance at recovery, thanks to two new procedures developed to restore the injured area, according to a study published in the July 2009 issue of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS).
The potential of forest biotechnology to help address significant social and environmental issues is being "strangled at birth" by the rigid opposition of some groups and regulations that effectively preclude even the testing of genetically modified trees, scientists argue in a new report.
Researchers have found that men and women who feel sensitive to rejection based on their physical appearance are more likely to express interest in having cosmetic surgery than those who are less sensitive to appearance-based rejection. This effect is particularly true when people recall negative comments about their physical appearance.
The results of the first Welsh GP patient survey have been published recently.
Today"s 65 year old Medicare Part D beneficiary will be 79 when the coverage gap, or "donut hole," is eliminated, says a new analysis of proposed legislation from the House of Representatives released today by Avalere Health. The firm also concludes that although fewer people will fall into the gap from now until 2023, by 2020 some of the sickest Medicare beneficiaries will spend upwards of $16,000 on drugs before reaching catastrophic coverage where the government covers 95% of their drug costs.
A new study of obese adolescents has shown that laparoscopic gastric banding surgery -- the "Lap-Band" procedure -- not only helps them achieve significant weight loss but can also improve and even reverse metabolic syndrome, reducing their risk for cardiovascular disease and diabetes.
Survivors of childhood cancer run particular risks when pregnant and should be closely monitored, the 25th annual conference of the European Society of Human Reproduction and Embryology heard today (Wednesday 1 July). Dr. Sharon Lie Fong, of the Department of Obstetrics and Gynaecology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands, said that, although such women may have conceived spontaneously and considered themselves to be perfectly healthy, their deliveries should always take place in a hospital.
A new study by a large international consortium found that many common genetic variants contribute up to a third of a person"s risk of inheriting
POZEN Inc. (NASDAQ:POZN), announced the submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for the marketing approval of VIMOVO™ (PN 400), the combination of enteric coated (EC) naproxen and immediate release esomeprazole. POZEN and AstraZeneca entered into a global co-development agreement for VIMOVO in August 2006. Pending regulatory approval, the proposed trade name is VIMOVO and the proposed indications are for the signs and symptoms of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis in patients who are at risk for developing NSAID-associated ulcers.
The pharmaceutical company Roche on Wednesday announced a program to help ensure developing countries have access to its antiviral Tamiflu, for "the management of a novel influenza strain defined by the WHO as having significant and current pandemic potential," Reuters reports (Egenter, 7/1). The program will make Tamiflu, which has been shown to be effective against the H1N1 (swine flu) virus, available to developing countries for "half the price normally charged," Dow Jones Newswires/Wall Street Journal reports (Mengewein, 7/1).
Alastair Campbell has won Mind"s Champion of the Year Award for his significant contribution to raising awareness of mental health. He beat fellow nominee and chat show host Paul O"Grady, among other mental health campaigners, to the prestigious award announced yesterday evening.
"Labor unions are showing their increasing displeasure over [health reform] financing proposals that target their healthcare benefits by launching attack ads against key lawmakers, causing the Senate"s leading advocate of taxing such benefits to seek an end to one especially aggressive campaign," Congress Daily reports. The Laborers" International Union of North America pulled an ad in Montana attacking Senate Finance Committee Chairman Max Baucus at the senator"s request, and after he asked to meet with the union"s president to discuss proposals (Dann, 6/30).
Health care is increasingly expensive, including for the insured, and many insurance plans offer only limited benefits and a false sense of security.
A diverse international network has proposed to significantly increase the
"Siblings are Special," a pilot prevention program targeting fifth graders and their younger siblings, recently received $1.45 million from the National Institute on Drug Abuse as part of the National Institutes of Health"s American Recovery and Reinvestment Act funding. The award is for two years.
Responding to scientists" need to measure organic contaminants in human body fluids, the National Institute of Standards and Technology (NIST) has recently made four new Standard Reference Materials (SRMs) available for purchase. Developed in collaboration with the Centers for Disease Control and Prevention (CDC), the human milk and serum SRMs have certified levels of contaminants, including flame retardants and pesticides, commonly found in the U.S. population. Scientists at the CDC and other laboratories will use the SRMs as controls in their experiments to ensure their methods are providing trustworthy results.
A scary unknown for many children, the prospect of surgery can cause intense preoperative anxiety. While some amount of stress is normal, what many parents do not know is that extreme anxiety before surgery can contribute to the occurrence of emergence delirium, a distressing incidence of acute behavioral changes experienced when "waking up" from anesthesia.
WHAT: Food prices rose by 5.5 percent in the past year and are expected to increase up to an additional 4 percent in 2009. Americans are seeking to get the most out of their dollar, and since together, dairy foods provide a unique package of nine essential nutrients, they are a nutritional bang for the buck.
For years, genes have been considered the one and only way biological traits could be passed down through generations of organisms.
New research at Rhode Island Hospital has uncovered the biological effects of a novel membrane estrogen receptor, a finding that has potential implications for hormonal therapy for breast cancer. The study is published in the July edition of the journal Molecular Endocrinology. This new study by Edward Filardo, MD, and his research team further supports earlier published work by the group that linked the transmembrane receptor, GPR30/GPER-1, to specific estrogen binding, rapid estrogen signaling and breast cancer metastasis. "What is exciting about this new work," says Filardo, "is that it provides some insight into the influence of GPR30 at the cellular level. It shows that estrogen action through GPR30 allows for breast tumor cell survival, and not breast tumor cell proliferation." Prior studies by Filardo"s group showed that estrogen acts through GPR30 to promote the rapid release of preformed growth factors that are tethered to the surface of breast cancer cells. Their latest study was conducted in an effort to better understand the mechanism by which GPR30 triggered the release of epidermal growth factor (EGF) polypeptides from the surface of breast cancer cells.
Dartmouth researchers have determined that movie characters who smoke, regardless of whether they are "good guys" or "bad guys," influence teens to try smoking. The study, published in the July 2009 issue of the journal Pediatrics, is titled "Adolescent Smoking: Who Matters More, Good Guys or Bad Guys?"
Deleting two genes in mice responsible for repairing DNA strands damaged by oxidation leads to several types of tumors, providing additional evidence that such stress contributes to the development of cancer. That"s the conclusion of a recent study* in DNA Repair by researchers at the National Institute of Standards and Technology (NIST), Oregon Health and Science University (OHSU) and the New York University School of Medicine (NYUSM).
A study published in the July 2009 issue of the Journal of Thoracic Oncology revealed that internet-based lung cancer information was of a higher quality in the United States (US) than in Japan. Dr. Yasushi Goto of the National Cancer Center Hospital in Tokyo and his team of researchers from both the US and Japan evaluated 150 Web sites and determined noticeable differences in the quality and type of information on lung cancer available over the internet in the two countries.
The salamander is a superhero of regeneration, able to replace lost limbs, damaged lungs, sliced spinal cord -- even bits of lopped-off brain.
A trio of genome-wide studies - collectively the largest to date - has pinpointed a vast array of genetic variation that cumulatively may account for at least one third of the genetic risk for schizophrenia. One of the studies traced schizophrenia and bipolar disorder, in part, to the same chromosomal neighborhoods.
A Decade-Long campaign by the British Psychological Society to have statutory regulation for practitioner psychologists comes to fruition.
The first of two reviews in this week"s edition of The Lancet discusses the standards of health and lifestyles of Indigenous people. It is the work of Professor Michael Gracey, of the Unity of First People of Australia, Perth, WA, Australia, and Professor Malcolm King, of the University of Alberta, Edmonton, Canada. There are almost 400 million Indigenous people in the world with low standards of health that are usually linked to malnutrition, poverty, environmental contamination, and prevalent infections. However, as those people shift to more modern or "western" lifestyles, conditions such as obesity, cardiovascular diseases, and type 2 diabetes have been on the rise. Physical, social and mental disorders related to misuse of alcohol and other drugs are also increasing. Indigenous people must be encouraged and given the means to take responsibility for issues that affect their health. In this review, the authors discuss indigenous people worldwide but focus on Aboriginal Australians.
Acura Pharmaceuticals, Inc. (Nasdaq: ACUR) and King Pharmaceuticals, Inc. (NYSE: KG) announced today that the U.S. Food and Drug Administration (FDA) has issued a Complete Response Letter regarding the New Drug Application (NDA) for Acurox (oxycodone HC1, USP and niacin, USP) Tablets CII, an immediate release product intended for the relief of moderate-to-severe pain.
Recent news reports have highlighted the importance of physician credentials and ensuring that physicians meet high standards in their chosen area of practice, according to the American Board of Medical Specialties (ABMS), which coordinates and assists its 24 Member Boards in their efforts to develop and implement educational and professional standards for the evaluation and certification of physician specialists. Certification by an ABMS Member Board is considered the gold standard in physician certification in the health care industry.
Eisai Co., Ltd. (Headquarters: Tokyo, President & CEO: Haruo Naito, "Eisai") and Eisai Corporation of North America (Headquarters: Woodcliff Lake, NJ, Chairman and CEO Hajime Shimizu) are currently focusing on three clinical development programs for the company"s major product Aricept(R) (donepezil hydrochloride tablets) to further contribute to patients with Alzheimer"s disease. As progress in those programs has been made, Eisai announces the status as follows:
Patients will continue to be unprotected if statutory independent regulation is not extended to counsellors and psychotherapists, according to leading national charities Mind and WITNESS. On the day that psychologists are to be regulated by the Health Professions Council (HPC), the charities welcome the advancement and urge counsellors and psychotherapists to follow suit.
Home remains the likeliest place to suffer an eye injury, according to a survey conducted by the American Academy of Ophthalmology (Academy) and the American Society of Ocular Trauma (ASOT). The annual Eye Injury Snapshot, a clinical survey of eye injuries across the U.S., conducted from May 17 to May 24 this year, found that nearly half (47.6 percent) of the 2.5 million eye injuries that Americans suffer annually now happen in and around the home in common places like the lawn, garden, kitchen or garage.
Independence Day and fireworks often go hand-in-hand. And even though fireworks have long been a tradition during this holiday, the American Optometric Association (AOA) cautions that they also carry the risk of serious injury to the eyes.
President Obama reiterated his call to adjust Medicare reimbursement rates as a part of his broad push for health reform in a meeting with nine reporters, including writers from local newspapers, Wednesday. "While steering clear of details, Obama indicated that revised reimbursement rates helpful to areas [where reimbursement rates are low] should be part of a comprehensive healthcare reform package now in the works," McClatchy reports. "The reforms should also help steer more physicians to medically underserved regions, he said," achieve better quality, and lower government payments. The news service notes that the meeting was "part of [Obama"s] effort to rally political support for a healthcare rewrite. The package is still a work in progress, as key congressional committees already have missed their self-imposed legislative deadlines" (Doyle, 7/1).
The American Pharmacists Association (APhA) advises consumers to take acetaminophen products as recommended on the labeling and seek guidance from pharmacists or other healthcare providers on evaluating medication options. This recommendation comes as the Food and Drug Administration (FDA) convened a public advisory committee meeting on June 29 and June 30, 2009 regarding acetaminophen use in both over-the-counter (OTC) and prescription (Rx) products, the potential for liver injury, and potential interventions to reduce the incidence of liver injury.
Planning for emergencies must take into account the growing numbers of frail elderly people who will by virtue of shifting demographics be involved in any natural or manmade disaster, according to US researchers writing in the International Journal of Emergency Management.
The Patients Doctors Don"t Know The New York Times
The following summarizes news coverage of state abortion statistics in Minnesota and Wisconsin.~ Minnesota: The number of abortions performed in Minnesota decreased for the second consecutive year in 2008, according to an annual report from the state Department of Health, the Minneapolis Star Tribune reports. Except for a one-time increase in 2006, the number of abortions in Minnesota has trended downward since a peak in 1980, when 19,028 procedures were performed. The new report found that 12,948 abortions were performed in the state in 2008, a decrease of 895 from 2007. Women ages 20 to 24 accounted for about one-third of the procedures, the most among any age group. The number of procedures among teenagers continued a decline that began in the 1990s but had leveled off slightly earlier this decade, the report found. The report also found that less than one-third of women reported using contraception and about one in seven was married at the time of conception (Von Sternberg, Minneapolis Star Tribune, 7/1).~ Wisconsin: Wisconsin abortion providers performed 8,229 procedures in 2008, the lowest number since the state began collecting statistics in 1974, according to an annual report by the state Department of Health Services, the AP/Milwaukee Journal-Sentinel reports. The number of abortions has declined annually since 2003, when 10,557 procedures were performed. State law requires abortion providers to provide DHS with the data. According to the report, slightly more than half of abortions took place in the first eight weeks of pregnancy. Women who had never been married accounted for about three-fourths of all procedures. The report found that 12% of abortions occurred among women ages 35 and older; 34% were among women ages 20 to 24; 11% were among women ages 18 and 19; and 6% were among girls ages 15 to 17. The number of abortions among minors decreased from 551 in 2007 to 500 in 2008, with parents providing consent in 452 of those cases (Richmond, AP/Milwaukee Journal-Sentinel, 6/30).