Cardiovascular
AMSA President Tiffany Fulde said, "It is unfortunate that the Commission has been unable to highlight specific strategies to recruit and retain more doctors into the bush. We currently have a health workforce in Australia that is grossly maldistributed, with large shortages of doctors and other health professionals in rural and remote Australia."
A new study by researchers at the Georgetown"s Lombardi Comprehensive Cancer Center finds a higher level of common household pesticides in the urine of children with acute lymphoblastic leukemia (ALL), a cancer that develops most commonly between three and seven years of age. The findings are published in the August issue of the journal Therapeutic Drug Monitoring.
The U.S. Food and Drug Administration issued a final regulation classifying dental amalgam and its component parts - elemental mercury and a powder alloy-used in dental fillings. While elemental mercury has been associated with adverse health effects at high exposures, the levels released by dental amalgam fillings are not high enough to cause harm in patients.
As they worked to move health care reform legislation through the Energy and Commerce Committee, House Democrats said they were close to a compromise with fiscally conservative Democrats, a group that so far has been a roadblock, The Hill reports.
Obama"s Plan Isn"t The Answer The Washington Post
Farmers are once again being urged to vaccinate their livestock against the threat of bluetongue. The warning from the Joint Action against Bluetongue campaign (JAB) comes as the country enters the height of summer meaning midge activity is reaching a peak period and the risk of a bluetongue incursion increases on a daily basis.
Cannabis Science Inc. (OTCBB: CBIS), an emerging pharmaceutical cannabis company, is pleased to report that the FDA has provided the Company with documentation to assist the Company to review and plan its initial applications to get its first drug into formal testing.
Illinois health officials contend that images seen in the media, social influences, and a lack of "frank" discussion on STDs in schools, among other issues, might be contributing to increases in STD rates across the state, the State Journal-Register reports. "According to recently released data, new cases of chlamydia in Illinois reached an all-time high statewide in 2008 - 59,169 - while the number of gonorrhea cases outside Chicago has been rising in recent years and totaled 10,165 in 2008," the Journal-Register reports. In addition, about 35,000 state residents have HIV/AIDS, the article states. Charlie Rabins, chief of the STD program at the Illinois Department of Public Health, said a bill (SB 212) currently awaiting Gov. Pat Quinn"s (D) approval might help reduce STD rates. The bill "would allow what is called "expedited partner therapy," in which medical professionals who treat patients for gonorrhea or chlamydia can give those patients single-dose antibiotics to pass on to sexual partners without first examining the partners," according to the Journal-Register (Olsen, 7/27).
The Baton Rouge Advocate on Sunday examined reasons behind Baton Rouge, La."s high AIDS rate. The most recent data from CDC ranks the Baton Rouge metro area third nationally for AIDS cases for 2007, with 31.4 cases per 100,000 people, according to the article. "State health officials, medical professionals and people who work in HIV/AIDS prevention say there are a variety of reasons the Baton Rouge metro area ranks near the top," including delayed testing, denial of high-risk behavior among individuals and medical advances that are allowing people to live longer with the virus, the Advocate reports. Beth Scalco, the Louisiana director of the HIV/AIDS Program for the state Office of Public Health, said the city"s close proximity to four prisons also contributes to the high rates. Arnold "A.J." Johnson, founder of the Baton Rouge AIDS Society, said the government does not adequately fund HIV/AIDS education in the area. He added, "Part of the problem is the culture and atmosphere. The government needs to come here and attack this area like they did when Hurricane Katrina hit" (Ward, 7/26).
Victorian researchers have developed a wristwatch that continuously monitors the health status of people with Parkinson"s disease to help doctors manage their treatment, Victorian Minister for Innovation Gavin Jennings said today.
Ventana Biotech Inc ("Ventana")(PINK SHEETS:VNTA), a biotechnology company that is developing a appetite-suppressing chewing gum, released detailed information about its innovative Anti-Obesity Chewing Gum.
The Healthcare Association of New York State (HANYS) called on the State Legislature to pass much-needed legislation that will better protect the rights of incapacitated patients and spare family members from the nightmare of helplessly watching their loved one"s health care wishes go unfulfilled.
Guns smuggled from the US arm criminals in Canada and Mexico, contributing to a higher murder rate in Canada and more intense drug crime conflict near the Mexican border, according to a study published in a special issue of Criminology and Criminal Justice, published by SAGE.
Elron Electronic Industries Ltd. (NASDAQ & TASE: ELRN) announced, that further to it previous announcement on July 28, 2009, Medingo Ltd., a group company held 92% by Elron and its subsidiary, RDC - Rafael Development Corporation Ltd., has received formal clearance from the Food and Drug Administration ("FDA"), to market its Solo™ MicroPump Insulin Delivery System in the United States.
Biotech firm Replikins Ltd. released its analysis of the June and July genomic data that predicts the rates of infectivity and lethality of the H1N1 (Swine Flu) virus. The quantitative analysis shows continued elevated levels in the Replikin Counts* of both Infectivity and Lethality genes, which indicate that the end of the current outbreak is not yet in sight.
CytRx Corporation (NASDAQ: CYTR), a biopharmaceutical research and development company engaged in the development of high-value human therapeutics, announced that results demonstrating that its cancer drug candidate INNO-206 caused statistically significant tumor shrinkage in an animal model of ovarian cancer have been accepted for publication in the peer-reviewed journal Investigational New Drugs. The manuscript based on this animal trial, "INNO-206, the (6-maleimidocaproyl hydrazone derivative of doxorubicin), shows superior antitumor efficacy compared to doxorubicin in different tumor xenograft models and in an orthotopic pancreas carcinoma model," was made available ahead of journal printing in electronic format in the January 8, 2009 on-line issue of Investigational New Drugs.
New evidence suggests that children who have a diet high in calcium and who consume dairy products may have a lower mortality rate compared with those who do not, according to research published ahead of print in the journal Heart.
There is no evidence that organically produced foods are nutritionally superior to conventionally produced foodstuffs, according to a study published in The American Journal of Clinical Nutrition.
A US study published online ahead of print in a leading medical journal suggests that complications from H1N1 swine flu could hit pregnant
Researchers at the University of Southern California (USC) have identified a critical molecular mechanism that allows the influenza virus to evade the body"s immune response system.
"You can think of Congress"s efforts to pay for health reform as being a little bit like a battle to slay a many-headed Hydra," writes the New York Times" economic columnist, David Leonhardt. Congress has floated idea after idea for paying for comprehensive health reform, but their proposals have failed to make ends meet because they "do not raise revenue as quickly as health costs rise." Most new taxes - such as a surtax on the rich proposed in the House - increase only as quickly as the economy, while health costs have inflated much more quickly over the last decade.
Patients being tested for HIV from a mouth swab placed in their mouth can now get their results in just 20 minutes.
China"s Deputy Health Minister Yin Li on Tuesday said that public health cooperation between China and the U.S. can improve the health of both countries and be strategically significant to world peace and development, Xinhua/China View reports (7/29).
"Three internationally known organizations based in St. Louis - the Donald Danforth Plant Science Center, the Washington University School of Medicine and St. Louis Children"s Hospital" - have entered into a partnership, known as the Global Harvest Alliance (GHA), which aims to "create inexpensive, nutritionally complete food to help the world"s hungry and undernourished," the AP/Google.com reports. Alliance researchers will focus on several of the most successful approaches used to combat malnutrition and attempt to further enrich foods already used to fight it. "In addition, the alliance aims to help testing and distribution of crops genetically modified to boost nutritional content. They hope to provide the crops cheaply to farmers to produce more nutritious foods," writes the AP/Google.com (Taylor, 7/29).
Over the past few years, MIT engineers have successfully tested robotic devices to help stroke patients learn to control their arms and legs. Now, they"re building on that work to help children with cerebral palsy.
If you"ve ever felt doomed to repeat your mistakes, researchers at MIT"s Picower Institute for Learning and Memory may have explained why: Brain cells may only learn from experience when we do something right and not when we fail.
A new article in the journal Risk Analysis assessed various ways in which aerosol transmission of the flu, a central mode of diffusion which involves breathing droplets in the air, can be reduced. Results show that face protection is a key infection control measure for influenza and can thus affect how people should try to protect themselves from the swine flu.
Better online support services for suicidal people is more important than shutting down websites showing ways to die, a research academic from The University of Queensland says.
The American Nurses Association (ANA) joins with the entire nursing community in mourning the passing of American Association of Nurse Anesthetists (AANA) interim Executive Director John Garde, CRNA, MS, FAAN. John Garde passed away last week from complications related to pancreatic cancer.
Recycling is a critical component in the process of transmitting information from one neuron to the next, and a large protein called Tweek plays a critical role, said an international consortium of researchers led by Baylor College of Medicine in a report in the current issue of the journal Neuron.
To learn from experience, it is essential to know whether a past action was associated with a desired outcome. Now, scientists have demonstrated how this information can be coded by a single cell. The research, published in the July 30th issue of the journal Neuron, provides strong support for a neural mechanism that allows reward signals to be combined over time to drive successful learning.
Rates of severe childhood obesity have tripled in the last 25 years, putting many children at risk for diabetes and heart disease, according to a report in Academic Pediatrics by an obesity expert at Brenner Children"s Hospital, part of Wake Forest University Baptist Medical Center.
The latest findings of the North Carolina-Louisiana Prostate Cancer Project reveal potential new targets for reducing racial disparities in prostate cancer survival and highlight the importance of the health care delivery system. The study reports differences in physician trust, access to care, and continuity of care between African American and Caucasian men which result in advanced prostate cancer at the time of diagnosis and contribute to the higher death rate among African American men. The study is published in the early view issue of Cancer online July 27, 2009.
[Why Great Britain"s success in Beijing could have been anticipated and why it should continue beyond 2012
Around one in five young people in the U.S. have a current mental, emotional, or behavioral disorder. About half of all adults with mental disorders recalled that their disorders began by their mid-teens and three-quarters by their mid-20s. Early onset of mental health problems have been associated with poor outcomes such as failure to complete high school, increased risk for psychiatric and substance problems, and teen pregnancy.
There are at least 100 ways to say, "It hurts!" And that is the problem.
The American Red Cross is pleased to announce five new additions to its National Celebrity Cabinet, a group of celebrity supporters who promote Red Cross services by donating their time, helping neighbors prepare for emergencies, responding to disasters and lending a helping hand to those in need.
The Committee for a Responsible Federal Budget urges policymakers to make controlling health care cost growth the focus of health care reform (see Principle #1: Slowing Health Care Cost Growth ).
A new analysis finds that women in New Jersey who take the breast cancer drug tamoxifen in conjunction with certain popular antidepressants may be at a higher risk for a breast cancer recurrence.
United Therapeutics Corporation (Nasdaq: UTHR) announced that the United States Food and Drug Administration (FDA) has approved TYVASO (treprostinil) Inhalation Solution for the treatment of pulmonary arterial hypertension (PAH) using the TYVASO Inhalation System (which includes the Optineb-ir device and accessories). TYVASO is indicated to increase walk distance in patients with NYHA Class III symptoms associated with WHO Group I PAH, which includes multiple etiologies such as idiopathic and familial PAH as well as PAH associated with scleroderma and congenital heart disease.
An estimated 428,000 residents in New Mexico could lose their private, employer-based coverage if Congress passes a House health reform bill, according to state-specific analysis of The American Affordable Health Choices Act of 2009 released this week by The Heritage Foundation.
More than 40 percent of the 120 million visits that Americans made to hospital emergency departments in 2006 were billed to public insurance, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.
As part of its study of how much vitamin D and calcium people need, a committee convened by the Institute of Medicine will hold a public workshop to gather insights and data from experts on Tuesday, Aug. 4. Among the workshop"s presentations will be a discussion of a recent vitamin D and calcium report released by the Agency for Healthcare Research and Quality, which can be found at http://www.ahrq.gov/clinic/tp/vitadcaltp.htm. A workshop agenda with a list of presentations is available at http://www.iom.edu/?id=68400.
With the implementation of the 48-hour working week for workers throughout Europe, including doctors, on 1 August 2009, the BMA in Northern Ireland has said that it will insist that the health service must meet its obligations to implement the European Working Time Directive (EWTD).
The International Diabetes Federation (IDF), International Union Against Cancer (UICC) and World Heart Federation (WHF) issued a joint statement that calls on the international community to address urgently the epidemic of non-communicable diseases (NCDs), responsible for 35 million deaths a year. The statement demands a substantial increase in funding for NCDs and greater availability of essential medicines, among other urgent responses, in a way to accelerate achievement of the health Millennium Development Goals.
The following summarizes recent research related to ovarian cancer.~ Early periods linked to lower survival: Women who start menstruating at an early age or experience more menstrual cycles over their lifetimes appear to have a lower chance of surviving ovarian cancer, according to a study published this month in the journal Cancer Epidemiology, Biomarkers, and Prevention, Reuters reports. For the study, researcher Cheryl Robbins and colleagues analyzed the medical data of 410 ovarian cancer patients who participated in the Cancer and Steroid Hormone study between 1980 and 1982. The analysis found that the women who had their first period before age 12 had a 51% greater risk of dying than the women who began menstruating at age 14 or older. The women who had the highest number of lifetime menstrual cycles had a 67% greater risk of dying during follow-up than the women with the lowest number of cycles (Reuters, 7/24).~ Lung cancer risk higher for women after hysterectomy with ovary removal: Women who have had hysterectomies in which their uterus and both ovaries are removed to prevent ovarian cancer appear to have a higher risk for developing lung cancer, according to researchers at the University of Montreal, the New York Times reports. The researchers discovered the connection while looking for links between lung cancer and hormones for a study published in May in the International Journal of Cancer. Although they did not find a relationship between lung cancer risk and hormonal factors such as menstruation patterns, child-bearing or breastfeeding, the researchers found that women who had medically induced menopause had 1.92 times greater risk of developing lung cancer than women who had natural menopause (Caryn Rabin, New York Times, 7/24).~ Small tumors present for years before detection: Minute-sized ovarian tumors form and remain in the Fallopian tubes for an average of four years before they grow large enough to be detected, which might suggest why ovarian cancer frequently is diagnosed in its later stages, according to a study published in the journal PLoS Medicine, Reuters reports. For the study, lead researcher Patrick Brown of Stanford University and the Howard Hughes Medical Institute and colleagues analyzed the tumors of women whose Fallopian tubes and ovaries were removed because they had family histories of and genetic risk for ovarian cancer. They found small tumors -- most less than three millimeters in diameter -- that previously had not been detected in the women. In a statement, Brown said, "There is a long window of opportunity for potentially lifesaving early detection of this disease, but the tumor spreads while it is still much too small to be detected by any of the tests that have been developed or proposed to date." According to Reuters, blood tests for the compound called CA-125 may help guide therapy but do not indicate whether a woman has a tumor (Reuters, 7/28).
The MS Society has responded to today"s Law Lords ruling concerning the case of Debbie Purdy, who has sought clarification on the law of assisted suicide.
This week long observation of the importance of breastfeeding is organized by the World Breastfeeding Week organization (worldbreastfeedingweek.org). The theme this year is the importance of breastfeeding during emergency situations. It is important that when natural or man-made disasters strike that all involved remember the importance of maintaining and supporting breastfeeding of infants affected by the disaster.
The National Institute for Health and Clinical Excellence (NICE) welcomes the referral of four clinical areas by the Department of Health following advice from the National Quality Board and will now begin work on setting NICE quality standards for the NHS using a pilot process.
America"s Health Insurance Plans (AHIP) released the following statement from spokesman Robert Zirkelbach.
Richard Chapman, from Selsdon, near Croydon, stood on Trafalgar Square"s Fourth Plinth yesterday from 9pm to 10pm to raise funds and awareness for Diabetes UK.
NHS staff will be vaccinated first in the Government"s swine flu vaccination campaign, followed by pregnant women, young children and adults with chronic illnesses, Pulse can exclusively reveal. Pulse has learned from a senior Government adviser that a "pecking order" has been drawn up for vaccination.
This month"s Ophthalmology, the journal of the American Academy of Ophthalmology, reports on the use of bevacizumab (Avastin) to benefit diabetic patients with macular edema as well as people who develop cystoid macular edema after cataract surgery. Bevacizumab is also used to treat some cancers. A third study describes methods that could make cataract surgery safer for diabetic retinopathy (DR) patients. DR is the major threat to vision in working-age people, a health issue that will only intensify if cases triple by 2050 as predicted.
Family service agencies are missing huge opportunities to help children by focusing only on mothers and ignoring fathers, according to a groundbreaking study by some of the nation"s top family and child development researchers.
Kaiser Health News reports that an agreement by House Democrats with fiscally conservative Blue Dog Democrats has a cadre of detractors, including "state officials worried about increased Medicaid costs and liberal lawmakers upset about a proposed reduction in subsidies for low-income families to buy insurance."
Health Affairs: Annual Medical Spending Attributable to Obesity: Payer- and Service-Specific Estimates -- Using data from 1998 and 2006 Medical Expenditure Panel Surveys (MEPS) - "a nationally representative survey of the civilian noninstitutionalized population that quantifies a person"s total annual medical spending by type of service and of payment" - the authors estimate the health cost of obesity in the U.S. is $147 billion. "Across all payers, per capita medical spending for the obese is $1,429 higher per year, or roughly 42 percent higher, than for someone of normal weight. In aggregate, the annual medical burden of obesity has increased from 6.5 percent to 9.1 percent of annual medical spending and could be as high as $147 billion per year (in 2008 dollars) based on the NHEA [National Health Expenditure Accounts] estimate," according to the study. In conclusion, the authors write, "The take-home message is that without a strong and sustained reduction in obesity prevalence, obesity will continue to impose major costs on the health system for the foreseeable future. And although health reform may be necessary to address health inequities and rein in rising health spending, real savings are more likely to be achieved through reforms that reduce the prevalence of obesity and related risk factors, including poor diet and inactivity" (7/27).
"The U.N. unveiled a multimillion dollar strategy a dozen years ago to save children worldwide, but a new [Lancet] study has found the program had surprisingly little effect in Bangladesh, one of the world"s poorest countries," the Associated Press reports. Since 1997, when the WHO and UNICEF launched the Integrated Management of Childhood Illness (IMCI) Program to help reduce the numbers of deaths in children under age 5 from diarrhea, pneumonia, measles and malnutrition, more than 100 countries have adopted the program, drawing upon "millions" in aid, according to the news service.
A study, "Prenatal Origins of Poor Sleep in Children," in the Aug.1 issue of the journal SLEEP found that alcohol consumption during pregnancy and small body size at birth predict poorer sleep and higher risk of sleep disturbances in 8-year-old children born at term. Findings are clinically significant, as poor sleep and sleep disturbances in children are associated with obesity, depressive symptoms, attention deficit hyperactivity disorder, and poor neurobehavioral functioning.
Patient satisfaction with their medications and the quality of interactions with their doctor reflect the success of gastroesophageal reflux disease (GERD) therapy, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association (AGA) Institute.
Transposons are mobile genetic elements found in the hereditary material of humans and other organisms. They can replicate and the new copies can insert at novel sites in the genome. Because this threatens the whole organism, molecular mechanisms have evolved which can repress transposon activity. Professor Klaus Förstemann of the Gene Center of Ludwig-Maximilians-Universität (LMU) in Munich and a team of researchers working with the fruitfly Drosophila melanogaster have now uncovered a new type of cellular defence that acts against DNA sequences present in high copy numbers inside the cell, even if they have not integrated into the genome. Small molecules of RNA (a class of nucleic acid closely related to the genetic material DNA) play the central role. "Transposons are genomic parasites, so to speak", says Förstemann. "If they are allowed to proliferate, the genome can become unstable or cancers can develop. We now want to find out whether mammalian cells possess this newly discovered defence mechanism and to elucidate precisely how it works." (EMBO Journal online, 30 July 2009.)
UroToday.com - A recent European study demonstrated that 10-year mortality from cardiovascular disease and cancer was decreased in a population of 70 to 90 year olds who adhered to a Mediterranean diet, were physically active, had moderate alcohol consumption and did not smoke. There are also reports suggesting an inverse association between physical activity and risk of prostate cancer (CaP). Yet mechanisms linking lifestyle and longevity are not well investigated. This report in The Prostate investigates an animal model for the association between physical activity and development of CaP.
By searching millions of DNA variations in the genomes of thousands of women with and without ovarian cancer, scientists have discovered a
Participants in the University of Wisconsin-Madison"s
Response Genetics Inc. (Nasdaq: RGDX), a company focused on the development and sale of molecular diagnostic tests for cancer, will announce the results of separate analyses of KRAS gene mutations and TS and RRM1 gene expression in non-small cell lung cancer (NSCLC) during the 13th World Conference on Lung Cancer, which will be held July 31 to August 4. Results will provide insights into which patient subtypes are most likely to benefit from the commonly prescribed chemotherapies pemetrexed and gemcitabine.
Parents of newborns who tip the scales at less than 5 ÷½ pounds should put some heavy thought to a possible future consequence: kidney disease. Low birth weight babies have a 70% greater risk of developing chronic kidney disease (CKD) in later life, according to research published in the August issue of the American Journal of Kidney Diseases, the official journal of the National Kidney Foundation.
As people age, the potential exists for those years to be the most rewarding and fulfilling time of their lives. However, major illness, retirement, the death of a spouse, and a shrinking circle of friends all may, in some cases, contribute to increased levels of stress and depression in the elderly. For that reason the chief of geropsychiatry for the Los Angeles Jewish Home - the largest single- provider of senior residential housing in the western United States - is offering seniors and their loved ones 10 warning signs that may trigger the need for assistance with mental health issues.
Brazos Valley residents, neuroscience researchers, and interested clinicians will each have opportunities to hear from internationally recognized researchers on the topic of aging and Alzheimer"s Disease during the Texas Brain and Spine Institute"s Third Annual Neuroscience Symposium on September 3 and 4. This year"s symposium will consist of an evening of public presentations aimed at helping local residents, Alzheimer"s patients, and their family members better understand early signs of the disease and ways to reduce your risk. The Friday afternoon session will feature a clinical presentation for health providers and researchers.
"A week-old agreement among House Democrats to smooth out disparities in the way Medicare reimburses rural and urban health providers is in danger of crumbling, as disputes erupted Friday over what actually was agreed to," The Wall Street Journal reports. "Some lawmakers from states with high health-care costs are also pressing House Democratic leaders for changes to the deal to ensure that their doctors and hospitals don"t see too big of a bite. ò€¦ Lawmakers from populous areas are questioning whether the deal on geographic disparities should be altered to allow more time for Medicare changes to take effect, since there is no longer the urgency of putting those changes into effect before the public option is rolled out. Another issue is for how long a period of time after changes go into effect urban hospitals should be "held harmless," meaning they won"t see their Medicare reimbursements cut" (Vaughan, 8/2).
A former Clinton administration official said last week that there aren"t enough doctors in America to handle the increase in patients if health reform covers more uninsured, NPR reports.
In an interview with the Seattle Post-Intelligencer, Washington state Insurance Commissioner Mike Kreidler called the American health system an out-dated, World War II-era obstacle to economic progress. "We"ve been talking about health-care reform in this country for over 100 years, and its never happened," he said. However, he added, "I believe that Congress will be successful." Kreidler, a Democrat, was a member of Congress in the 1990s, when the Clinton administration attempted an overhaul. This time around, he said, "We"re still in July, and they"re making huge progress" (Pulkkinen, 8/2).
A new deal to balance California"s budget may have serious repercussions for the health of the state"s children, while South Carolina grapples with health cuts of its own. Meanwhile, New Jersey may become one of the first states to publically disclose hospital errors.
A Wilmington News Journal editorial discussed the potential lifting of the ban on using federal funding for needle exchange programs. The editorial notes recent Congressional action and the restrictions in a House bill that prohibit needle exchanges to operate "within a 1,000 feet of day care centers, schools, parks, playgrounds, pools and youth centers." According to the News Journal, "This rule wipes out much of the flexibility many cities need in their fight to prevent the spread of HIV among intravenous drug users. The nation"s capital, where the rates of HIV and AIDS cases are considered epidemic, would be hit the hardest because no part of the District of Columbia would be eligible for the funding according to AIDS Action." The editorial adds, "Vans patrolling near vulnerable populations - specifically young, impressionable children - are an issue that must be addressed. But well-intentioned limits should not be allowed to hold up the rest of the program," according to the News Journal (8/1).
Identification of criteria for the detection of prolonged grief disorder
A new diagnostic tool developed by Van Andel Research Institute (VARI) scientists has shown promising results when used with patients of pancreatic cancer, one of the deadliest forms of cancer due to the difficulty of diagnosing it in its early stages. The method, which studies carbohydrate structures in the bloodstream, could lead to the development of blood tests that can detect cancer more effectively.
Heavy drinkers of beer and spirits face a much higher risk of developing cancer than the population at large, says a group of Montreal epidemiologists and cancer researchers. Their findings show that people in the highest consumption category increased their risk of developing oesophageal cancer sevenfold, colon cancer by 80% and even lung cancer by 50%.
BMA Cymru Wales on Monday launched a campaign aimed at improving the working lives of junior doctors in Wales.
Anorexic patients drastically reduce food intake and are often not capable of changing their behavior. This can lead to life-threatening weight loss. Using MRI technology, scientists at Heidelberg University Hospital have discovered for the first time processes in brain metabolism that explain this disturbed eating behavior.
Almost all organisms evolve from a single cell, a fertilised egg. In the first hours after fertilisation, the fate of its future development is determined. It is dictated by the separation of cells that will become sperm and ovules - germ cells-, from the remaining cells, which will be responsible for forming the body - organs and tissues -, and that comprise the somatic cell line. Scientists at the Institute for Research in Biomedicine (IRB Barcelona), headed by Jordi Casanova, research professor at CSIC, have identified the mechanism that protects somatic cells against the behaviour of germ cells. When this mechanism fails, the embryo dies. Made in the fruit fly Drosophila melanogaster, this finding could be universal. This research was published yesterday in the advanced online edition of EMBO Reports.
UK clinical research is currently benefiting from significant additional investment from Government and other research funders. A challenge for funders and institutions is to allocate res across the range of clinical academic specialties, to most effectively pursue research and its translation into improved healthcare.
La Jolla Institute for Allergy and Immunology researchers studying an enzyme believed to play a role in allergy onset, instead have discovered its previously unknown role as a tumor suppressor that may be important in myeloproliferative diseases and some types of lymphoma and leukemia. Myeloproliferative diseases are a group of disorders characterized by an overproduction of blood cells by the bone marrow and include chronic myeloid leukemia. Lymphoma and leukemia are cancers of the blood.
Congressman Michael C. Burgess, M.D. (R-Texas) sent a letter to President Obama yesterday accepting his invitation to "come over to the White House and go over line-by-line" the health care reform plan the President is pushing.
A determined effort by Audiology teams across the country has led to 99% of people receiving hearing aids or other appropriate treatment within the government"s 18-week target. Figures for February 2009, just released by the Department of Health, show that the situation has been improving every month since April 2008. The improvements have come about as a result of re-instating frozen posts combined with a determined effort by Audiology teams to work in more flexible and creative ways.
UCLA scientists have discovered a way to measure the amount of amyloid beta that is being absorbed by immune cells in the blood. Amyloid beta forms the plaques considered the hallmark of Alzheimer"s disease, and if the immune system isn"t adequately clearing amyloid beta, it may indicate Alzheimer"s risk, according to the researchers.
Heart specialists at St. Joseph Hospital in Orange, Calif. have performed a new procedure in which they repaired a hole in the patient"s heart through a tiny incision, offering the patient a much safer alternative verses open heart surgery.
Researchers at the University of Pittsburgh School of Medicine have learned that some healthy people naturally developed an immune response against a protein that is made in excess levels in many cancers, including breast, lung, and head and neck cancers. The finding suggests that a vaccine against the protein might prevent malignancies in high-risk individuals.
WHAT: The Nutrient-Rich Foods (NRF) Index is a new, objective, science-based way to measure the total nutritional quality of foods and beverages.
The Department of Health and Human Services has created a web site called "Ask Medicare" to help caregivers navigate the often confusing Medicare system. CNN reports on the experience of Kim Mickens, a caregiver who used the site to help her mother, who has Alzheimer"s disease. "Medicare personnel helped her get some of the medical supplies she needed and also recommend a new Web site called Ask Medicare. Designed to give easy access to people taking care of elderly relatives, Ask Medicare provides information and links to services that are important to caregivers."
PAHO on Monday announced it had found Tamiflu-resistant H1N1 (swine) flu along the Texas-Mexico border, Agence-France Press reports. The discovery of several cases in El Paso and McAllen, Texas, adds the U.S. to a growing list of countries with antiviral-resistant H1N1, such as Canada, Denmark, Hong Kong and Japan. "Experts had gathered in La Jolla on Monday to discuss the response to the outbreak, and warned that resistant strains were likely emerging because of overuse of antivirals like Tamiflu," the news service writes (8/3).
The Guardian examines British Prime Minister Gordon Brown"s offer "to help some of the world"s poorest countries to make healthcare free - starting with pregnant women and children - in a push to widen access to doctors across Africa and Asia." According to the newspaper, the "Department for International Development (DfID) is among the largest donors to many developing countries, and has pledged to spend 6 billion pounds [about $10.2 billion] on health by 2015. Brown hopes to use an expanding aid budget to influence the way public services are delivered on the ground."
The National Institutes of Health is launching the first integrated, drug development pipeline to produce new treatments for rare and neglected diseases. The $24 million program jumpstarts a trans-NIH initiative called the Therapeutics for Rare and Neglected Diseases Program, or TRND.
The Mount Sinai Medical Center has a new re center for prostate cancer treatment. Led by David B. Samadi, M.D., Chief of the Division of Robotics and Minimally Invasive Surgery in the Department of Urology, the new state-of-the-art facility at 625 Madison Avenue in New York City specializes in pre- and post-surgery care for patients who undergo a robotic prostatectomy at Mount Sinai"s main campus. It also provides expertise in the treatment of other urologic cancers, including bladder and kidney. A multilingual staff offers assistance with patient travel arrangements, accommodations, and translation services when required.
Celera Corporation (NASDAQ:CRA) announced yesterday the presentation of data replicating its novel mass spectrometry-based approach to identify and validate circulating protein biomarkers that detect non-small cell lung cancer (NSCLC) in an independent cohort of individuals with lung cancer. This study was performed in collaboration with scientists at NYU Langone Medical Center, NY. A key outcome of the study was the validation of a 9 biomarker immunoassay on a cohort of samples that is enriched for stage I disease, important for screening of early stage disease. The assay detected lung cancer with 92% sensitivity at 93% specificity. The panel also accurately distinguished malignant cases from benign lung disease. The data is being presented at the 13th World Conference on Lung Cancer as part of the International Association for the Study of Lung Cancer (IASLC) in San Francisco, CA.
A new US study has added to existing knowledge about the million or so brain cells in our gut by using lab mice to show that it can also grow
Cancer Centers of North Carolina, an affiliate of US Oncology, Inc., continues to offer cutting-edge treatment options to its patients through the addition of High Dose Rate (HDR) brachytherapy. This latest advance in brachytherapy allows physicians to deliver precise radiation treatment to a patient"s cancerous tumor and is rapidly becoming the treatment of choice for certain types of cancer.
NeurogesX, Inc. (Nasdaq: NGSX), a biopharmaceutical company focused on developing and commercializing novel pain management therapies, announced that the United States Food and Drug Administration (FDA) has extended the Prescription Drug User Fee Act (PDUFA) date from August 16, 2009 to November 16, 2009 to review the new drug application (NDA) for Qutenza(TM) to manage pain associated with postherpetic neuralgia (PHN).
Both combination and sequential single-agent chemotherapy are reasonable options to treat metastatic breast cancer, but the choice between the two should ultimately be based on patient- and disease-related factors, according to a new commentary published online August 5 in the Journal of the National Cancer Institute.
The English word "health" comes from the Old English word hale, meaning "wholeness, a being whole, sound or well,". Hale comes from the Proto-Indo-European root kailo, meaning "whole, uninjured, of good omen". Kailo comes from the Proto-Germanic root khalbas, meaning "something divided". Medilexicon"s medical dictionary has three definitions for health, the first being "The state of the organism when it functions optimally without evidence of disease or abnormality" (click here to read the other two).
The addition of the anaesthetic lidocaine to radiocolloid injection for sentinel- lymph-node (SLN) mapping in patients with early breast cancer reduces injection pain and improves patient comfort without compromising SLN identification, and should be introduced as standard practice, concludes an Article published Online First and in the September edition of The Lancet Oncology.
The fifth annual report card from the Washington, D.C.,-based Appleseed Center for Law and Justice examining the district"s response to HIV gives the city "high marks for rapid testing, interagency coordination, surveillance and fighting the disease in the D.C. Jail," but finds that the city falls short in other areas, the Washington Examiner reports (Neibauer, 8/5). "The government also received above-average grades for leadership, managing grants to groups that help people with the illness, and monitoring the effectiveness of those programs," the Washington Post reports. However, "While Mayor Fenty and his administration deserve recognition for the continued support of ò€¦ numerous [HIV/AIDS Administration] initiatives, his public appearances and statements about the epidemic have fallen short of his enthusiasm for action inside the government," the report said. The report added that the district could do more to address HIV and recommended that HAA assess whether the improvements they have made are reducing the spread of the virus, according to the Post (Fears, 8/5).
A team of US scientists has for the first time unravelled the entire genetic code of HIV, the virus that causes AIDS, paving the way for a better understanding of how these types of viruses
Timberline Knolls, one of the country"s leaders in the treatment of eating disorders, is recognizing well-known tennis star, Monica Seles, for disclosing her history with an eating disorder in her new book Get a Grip. Ms. Seles" display of courage and candor has the potential to help many others who have similar struggles, especially young female athletes.
Altair Therapeutics, Inc., a privately-held, biopharmaceutical company developing novel therapeutics for respiratory diseases, reported results from its phase I study evaluating the safety, tolerability and pharmacokinetics of its lead product, once-weekly inhaled AIR645, in healthy volunteers. AIR645 is a non-steroidal dual inhibitor of cellular responses to interleukin (IL)-4 and IL-13, cytokines that play a critical role in development and progression of asthma, rhinitis and other allergic disorders. Results presented today at the 2009 International Conference of the American Thoracic Society (ATS) within the Mini-Symposium "New Treatment Approaches for Asthma and Allergy" showed that inhaled AIR645 was safe, well tolerated and had dose-dependent exposure in the airways. These results demonstrate the potential of AIR645 as a convenient once-weekly treatment for asthma and other respiratory disorders. Later this year, Altair plans to initiate a phase II efficacy study in patients with asthma.
Rexahn Pharmaceuticals, Inc. (NYSE Amex: RNN), announced that it has enrolled 50% of the total projected enrollment required for its Phase IIa trial to evaluate the safety and preliminary efficacy of Serdaxin™ as a central nervous system based treatment for Major Depressive Disorder (MDD). The complete trial calls for the enrollment of up to 80 patients at multiple clinical trial sites in the United States.
ViraCor Laboratories, the leader in molecular diagnostic testing for infectious diseases, announced the launch of a new ultrasensitive molecular test to detect JC Virus in cerebral spinal fluid (CSF). The second JCV test to be developed in ViraCor"s laboratories, the ultrasensitive JCV PCR test can accurately detect the virus in a patient sample with as few as 25 viral copies per milliliter of sample.