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FDA Advisory Committee Votes In Favor Of Zyprexa For Two Adolescent Indications

Lilly) This press release contains forward-looking statements about Zyprexa. These statements reflect management"s current beliefs; however, as with any pharmaceutical product there are risks and uncertainties in the process of research and development, regulatory review, and commercialization. There is no guarantee that Zyprexa will be approved for the acute treatment of schizophrenia or manic or mixed episodes associated with bipolar I disorder in adolescents, or that, if approved, it will be commercially successful. For further discussion of these and other risks and uncertainties, see Lilly"s filings with the United States Securities and Exchange Commission. Lilly undertakes no duty to update forward-looking statements. References (1) The National Institute for Mental Illness. "About Mental Illness: Early Onset Schizophrenia." (2) The Child & Adolescent Bipolar Foundation. About Pediatric Bipolar Disorder. (3) The National Institute of Mental Health. About Mental Illness: Bipolar Disorder. (4) The National Institute of Mental Health. What is Schizophrenia? (5) Loranger, AW (1984): Sex difference in age of onset of schizophrenia. Archives of General Psychiatry; 41: 157-161 (6) Fleischhaker, C. et al. Long-term Course of Adolescent Schizophrenia. Schizophrenia Bulletin 2005 31(3):769-780; doi:10.1093/schbul/sbi014. (7) Kessler RC, Chiu WT, Demler O, Walters EE. Prevalence, severity, and comorbidity of twelve-month DSM-IV disorders in the National Comorbidity Survey Replication (NCS-R). Archives of General Psychiatry, 2005 Jun;62(6):617-27. (8) Mauricio Tohen et al. (2007). Olanzapine versus Placebo in the Treatment of Adolescents with Bipolar Mania. Am J Psychiatry 2007, 164: 1547-1556 (9) Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, pg. 385. (10) Korn, M. (2002). Building Foundations Toward Recovery in Bipolar Disorder. How Prevalent are Mood Disorders in Children and Adolescents? (11) Axelson D et al. (2006). Phenomenology of children and adolescents with bipolar spectrum disorders. Archives of General Psychiatry; 63(10):1139-48. Eli Lilly and Company

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