Popular Articles

Computer System For Dementia Patients
The labour force in the health services is shrinking, there are more and more old people, and a very high proportion of them are plagued by deteriorating short- and long-term memory. All this has created a need for computer-based solutions that will enable elderly people to live safely in their own homes, but at the same time, the technology needed to take special care of them is expensive. On top of this, different standards for home sensors create problems.
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National Medical Societies Offer Tips To Prevent Injuries; Children Often Victims
- Using a lawn mower can be as routine as bike riding or barbeques during spring and summer months. But often, people find themselves in terrifying situations with these seemingly safe household machines. In fact, 200,000 people - 16,000 of them children - are injured in lawn mower-related accidents each year, the U.S. Consumer Product Safety Commission reports. However, lawn mowers don"t "attack" on their own. Most injuries - such as severed fingers and toes, limb amputations, broken bones, burns and eye injuries - are caused by careless use and can be prevented by following a few simple safety tips.
News of the day
National Athletic Trainers' Association (NATA) Offers Guidelines For Management Of Serious Spine Injuries On The Athletic Playing Field
According to a new position statement from the National Athletic Trainers" Association (NATA), proper management of acute spinal injuries on the athletic playing field is crucial, given that sports participation constitutes the second most common cause of spinal cord injuries for Americans age 30 and younger. Sports medicine providers and others on the sidelines need to be familiar with the appropriate acute-management guidelines for athletes with cervical-spine injuries. Published in this month"s Journal of Athletic Training, NATA"s scientific publication, the position statement provides detailed guidelines for the immediate treatment and transport of athletes who are injured on the playing field.
Medical Devices

POZEN Submits New Drug Application For VIMOVO™ (PN 400)

POZEN Inc. (NASDAQ:POZN), announced the submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for the marketing approval of VIMOVO™ (PN 400), the combination of enteric coated (EC) naproxen and immediate release esomeprazole. POZEN and AstraZeneca entered into a global co-development agreement for VIMOVO in August 2006. Pending regulatory approval, the proposed trade name is VIMOVO and the proposed indications are for the signs and symptoms of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis in patients who are at risk for developing NSAID-associated ulcers. The NDA submission is based on data from a comprehensive clinical trials program. POZEN conducted two pivotal studies (301/302) under a special protocol assessment agreed with the FDA, which met their primary endpoints. In the 301/302 studies, significantly fewer subjects taking VIMOVO experienced endoscopically confirmed gastric ulcers compared to subjects receiving EC naproxen. The primary endpoint was the cumulative incidence of gastric ulcers through six months. In each of the trials, approximately 400 subjects received either VIMOVO or EC naproxen (500 mg), twice daily, over a six-month treatment period. Subjects underwent upper endoscopies at baseline and at one, three, and six months. Upon the FDA"s acceptance for filing of the NDA, a $10 million milestone payment from AstraZeneca will be payable to POZEN. About Osteoarthritis Osteoarthritis (OA) is a degenerative joint disease caused by the breakdown and eventual loss of the cartilage of one or more joints. Osteoarthritis is the most common form of arthritis and the most common cause of chronic pain, affecting nearly 140 million individuals worldwide,1 and impacting approximately 18% of women and 9.6% of men aged 60 and above.2,3 A combination of factors can contribute to osteoarthritis, including being overweight, aging, joint injury or stress, heredity and muscle weakness.4 Osteoarthritis commonly affects the hands, feet, spine or large weight-bearing joints, such as the hips and knees.5 In the U.S., the average direct cost of osteoarthritis is about $2,600 per year out-of-pocket expenses. Total annual disease costs are $5,700 (2000) and job-related osteoarthritis costs are $3.4 to $13.2 billion per year.6 POZEN


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