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'Homework Assignment' Could Mean Success, Failure For Health Reform Legislation
How well health care industry groups follow through on their "homework assignment" from President Obama to submit specific plans by early June on how they intend to reduce health care spending growth by $2 trillion over the next decade could determine whether current attempts to develop health care overhaul legislation are successful, the AP/Contra Costa Times reports (Alonso-Zaldivar, AP/Contra Costa Times, 5/25).In a letter that was sent to Obama on May 10, a coalition of health care industry groups wrote, "We will do our part to achieve your administration"s goal of decreasing by 1.5 percentage points the annual health care spending growth rate. ... This represents more than a 20% reduction in the projected rate of growth." The letter -- which was signed by the American Medical Association, the American Hospital Association, Pharmaceutical Research and Manufacturers of America, the Advanced Medical Technology Association, America"s Health Insurance Plans and the Service Employees International Union -- did not elaborate on what specific measures the groups would take to achieve such reductions. The Obama administration requested specifics on the coalition"s cost-cutting plans by June 1 (Kaiser Daily Health Policy Report, 5/18).Each group has been looking into its own ways it can reduce spending growth, the AP/Contra Costa Times reports. Insurers currently are examining strategies to cut the administrative costs of filing claims. AMA President-elect James Rohack said his organization will look at how to implement comparative effectiveness research and ways to prevent harmful and costly drug interactions, which he said "can save money ... by preventing unnecessary readmissions to hospitals," adding, "The most costly site where patients get care is the hospital." In addition, hospitals have begun looking into how to reduce readmissions.If the industry groups are able to convince lawmakers that their plans can significantly reduce spending growth, Obama "could be well on his way to closing a deal with Congress" on universal health coverage, the AP/Contra Costa Times reports. However, if the plans are rejected, the groups risk their reputations and Obama could be "seen as naive for entertaining such promises," according to the AP/Contra Costa Times. Some experts have said that the groups" pledge to cut health care spending is possible "in theory." According to the AP/Contra Costa Times, the challenge will be to persuade medical providers "to change years of ingrained habits that lead to much of the wasteful spending" in the health care system (AP/Contra Costa Times, 5/25). AHIP"s Ignagni Profiled
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Marking Anorexia With A Brain Protein
Eating disorders are frequently seen as psychological or societal diseases, but do they have an underlying biological cause? A new study shows that the levels of a brain protein differ between healthy and anorexic women.
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Emphasis On Self-Awareness And Personal Will In Groundbreaking 'Reorganizational Healing' Model
Reorganizational Healing (ROH), an emerging concept for wellness, healing, and personal growth, is explored in depth in a seminal groundbreaking article and accompanying commentaries in the latest issue of The Journal of Alternative and Complementary Medicine, a peer-reviewed journal published by Mary Ann Liebert, Inc. The Reorganizational Healing articles are available free online at http://www.liebertpub.com/acm.
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NPs-NPR-B/pGC-cGMP Signal Pathway Is Involved In Diabetic Gastroparesis

The natriuretic peptide (NP) receptor type B (NPR-B) gene was expressed in gastric smooth muscles of normal and diabetic rats and the expression was increased in diabetic rats. These results suggest that natriuretic peptide-dependent pGC-cGMP signal is up-regulated and it may contribute to diabetic gastroparesis in STZ-induced diabetic rat. Gastroparesis (delayed gastric emptying) is frequent in diabetic patients. It is a well-recognized complication of long-standing diabetes. Symptoms of diabetic gastropathy can range from mild dyspepsia to recurrent vomiting and abdominal pain and may progress to irreversible end-stage gastric failure known as gastroparesis. Gastroparesis seriously affects the quality of life. There is deterioration in glycemic control and incapacitating symptoms such as malnutrition, water and electrolyte imbalance, and aspiration may occur. However, the pathophysiology of diabetic gastropathy and gastroparesis, including impaired fundic and pyloric relaxation and impaired electrical pacemaking, is still not delineated. A research article published in volume 15, May 7, 2009 in the World Journal of Gastroenterology addresses this problem. The research team led by Professor Zheng Lin from Department of Physiology, Yanbian University College of Medicine, used physiological, radioimmunoassy and histochemistry techniques to study the role of the NPs-NPR-B/pGC(particulate guanylate cyclase)-cGMP signal pathway in the pathophysiology of diabetic gastropathy and gastroparesis in streptozotocin (STZ)-induced diabetic rats. This study has indicated that the CNP-induced relaxation and the production of cGMP of gastric smooth muscle were potentiated in STZ-induced diabetic rats. In addition to the activity of pGC, the expression of NPR-B mRNA in gastric smooth muscle was up-regulated in diabetic rats. These results suggest that the CNP-(NPR-B)-pGC-cGMP signal pathway may be involved in the pathogenesis of diabetic gastroparesis. Reference: Cai YL, Xu DY, Li XL, Qiu ZX, Jin Z, Xu WX. C-type natriuretic-peptide-potentiated relaxation response of gastric smooth muscle in streptozotocin-induced diabetic rats. World J Gastroenterol 2009; 15(17): 2125-2131 http://www.wjgnet.com/1007-9327/15/2125.asp Correspondence to: Zheng Jin, Department of Physiology, Yanbian University School of Medicine, 1829 Juzi Rd, Yanji 133000, Jilin Province, China. Lin Tian World Journal of Gastroenterology


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