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FDA Advisory Committee Votes In Favor Of Zyprexa For Two Adolescent Indications
The U.S. Food and Drug Administration (FDA) Psychopharmacologic Drugs Advisory Committee (PDAC) voted that Zyprexa(R) (olanzapine), an atypical antipsychotic, is effective and acceptably safe for the acute treatment of schizophrenia or manic or mixed episodes associated with bipolar I disorder in adolescents aged 13-17 years old. The panel supported the FDA and Lilly"s position that if Zyprexa is approved for the two indications, prescribers should consider other treatment options first for adolescent patients.
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ACMG Joins Lawsuit Challenging Patents On Breast Cancer Genes
The American College of Medical Genetics (ACMG) has joined the Association for Molecular Pathology, the College of American Pathologists, and the American Society for Clinical Pathology in a lawsuit filed today charging that patents on the human genes associated with breast and ovarian cancer interfere with diagnostic testing, stifle research and limit women"s options regarding their health care. The lawsuit challenges patents on the BRCA1 and BRCA2 genes, which are responsible for most cases of hereditary breast and ovarian cancers. Because these genes are "products of nature," the ACMG believes that granting patents on them is illegal.
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Men And Women Find Cosmetic Surgery Appealing When They Suffer Appearance-Based Rejection Sensitivity
Researchers have found that men and women who feel sensitive to rejection based on their physical appearance are more likely to express interest in having cosmetic surgery than those who are less sensitive to appearance-based rejection. This effect is particularly true when people recall negative comments about their physical appearance.
Endocrinology

Heavy, Daily Drinking Increases Risk Of High-Grade Prostate Cancer; Makes Preventive Drug Ineffective

Current research is inconclusive regarding the relationship between alcohol consumption and prostate cancer risk. Researchers led by Zhihong Gong Ph.D. of the University of California San Francisco, examined the associations of total alcohol, type of alcoholic beverage, and drinking pattern with risks of total, low- and high-grade prostate cancer. They used data from more than 10,000 men participating in the Prostate Cancer Prevention Trial (PCPT). They found participants who reported heavy alcohol consumption (ò‰¥50 g alcohol/day) and regular heavy drinking (ò‰¥4 drinks/day on ò‰¥5 days per week) were twice as likely or more to be diagnosed with high-grade prostate cancer (RR: 2.01, and 2.17, respectively). Less heavy drinking was not associated with risk. They also compared drinking patterns with treatment outcome among men enrolled on this placebo-controlled trial of the drug finasteride. They found finasteride"s ability to lower prostate cancer risk was blocked in men drinking Article: "Alcohol Consumption, Finasteride and Prostate Cancer Risk: Results from the Prostate Cancer Prevention Trial." Zhihong Gong, Alan R. Kristal, Jeannette M. Schenk, Catherine M. Tangen, Phyllis J. Goodman, and Ian M. Thompson. CANCER; Published Online: July 13, 2009 (DOI: 10.1002/cncr.24423); Print Issue Date: August 15, 2009 University of California San Francisco


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